I've been using a 200x201 size Bitmap in CP 5.0.0. At the moment this can only be manipulated by setting individual pixels. This is taking 2.3 seconds on an Adafruit CLUE to assign 0 (the transparent colour from my pallete) to each pixel.
I thought I'd try assigning a full size zero array.array but I ran out of memory. I then tried a row by row approach using slices and got NotImplementedError: Slices not supported.
I could do with a fill() method (implemented in C) a bit like the neopixel library has, that would let me do an efficient clear.