diff --git a/boards/waveshare/rp2040_plus/Kconfig b/boards/waveshare/rp2040_plus/Kconfig
index 18f7b99232b66..08687c89dda80 100644
--- a/boards/waveshare/rp2040_plus/Kconfig
+++ b/boards/waveshare/rp2040_plus/Kconfig
@@ -2,4 +2,9 @@
 # SPDX-License-Identifier: Apache-2.0
 
 config BOARD_RP2040_PLUS
+	bool
+	select RP2_FLASH_W25Q080
+
+config BOARD_RP2040_PLUS_16MB
+	bool
 	select RP2_FLASH_W25Q080
diff --git a/boards/waveshare/rp2040_plus/Kconfig.defconfig b/boards/waveshare/rp2040_plus/Kconfig.defconfig
index 00b2c0b2402fa..d23db7048db41 100644
--- a/boards/waveshare/rp2040_plus/Kconfig.defconfig
+++ b/boards/waveshare/rp2040_plus/Kconfig.defconfig
@@ -1,7 +1,7 @@
 # Copyright (c) 2025 David Schneider
 # SPDX-License-Identifier: Apache-2.0
 
-if BOARD_RP2040_PLUS
+if BOARD_RP2040_PLUS || BOARD_RP2040_PLUS_16MB
 
 if I2C_DW
 
@@ -10,4 +10,4 @@ config I2C_DW_CLOCK_SPEED
 
 endif # I2C_DW
 
-endif # BOARD_RP2040_PLUS
+endif # BOARD_RP2040_PLUS || BOARD_RP2040_PLUS_16MB
diff --git a/boards/waveshare/rp2040_plus/Kconfig.rp2040_plus_16mb b/boards/waveshare/rp2040_plus/Kconfig.rp2040_plus_16mb
new file mode 100644
index 0000000000000..090fb496a8a20
--- /dev/null
+++ b/boards/waveshare/rp2040_plus/Kconfig.rp2040_plus_16mb
@@ -0,0 +1,5 @@
+# Copyright (c) 2025 David Schneider
+# SPDX-License-Identifier: Apache-2.0
+
+config BOARD_RP2040_PLUS_16MB
+	select SOC_RP2040
diff --git a/boards/waveshare/rp2040_plus/board.yml b/boards/waveshare/rp2040_plus/board.yml
index 7e3e098fa81d4..387a170b47a87 100644
--- a/boards/waveshare/rp2040_plus/board.yml
+++ b/boards/waveshare/rp2040_plus/board.yml
@@ -1,6 +1,11 @@
-board:
-  name: rp2040_plus
-  full_name: RP2040-Plus
-  vendor: waveshare
-  socs:
-  - name: rp2040
+boards:
+  - name: rp2040_plus
+    full_name: RP2040-Plus
+    vendor: waveshare
+    socs:
+      - name: rp2040
+  - name: rp2040_plus_16mb
+    full_name: RP2040-Plus-16MB
+    vendor: waveshare
+    socs:
+      - name: rp2040
diff --git a/boards/waveshare/rp2040_plus/rp2040_plus_16mb.dts b/boards/waveshare/rp2040_plus/rp2040_plus_16mb.dts
new file mode 100644
index 0000000000000..2e041f460bb4e
--- /dev/null
+++ b/boards/waveshare/rp2040_plus/rp2040_plus_16mb.dts
@@ -0,0 +1,5 @@
+#include "rp2040_plus.dts"
+
+&flash0 {
+	reg = <0x10000000 DT_SIZE_M(16)>;
+};
diff --git a/boards/waveshare/rp2040_plus/rp2040_plus_16mb.yaml b/boards/waveshare/rp2040_plus/rp2040_plus_16mb.yaml
new file mode 100644
index 0000000000000..7c6a3b01e0dbc
--- /dev/null
+++ b/boards/waveshare/rp2040_plus/rp2040_plus_16mb.yaml
@@ -0,0 +1,23 @@
+identifier: rp2040_plus
+name: Waveshare RP2040-Plus
+type: mcu
+arch: arm
+flash: 16384
+ram: 264
+toolchain:
+  - zephyr
+  - gnuarmemb
+supported:
+  - uart
+  - gpio
+  - adc
+  - i2c
+  - spi
+  - hwinfo
+  - watchdog
+  - pwm
+  - flash
+  - dma
+  - counter
+  - clock
+  - usbd
diff --git a/boards/waveshare/rp2040_plus/rp2040_plus_16mb_defconfig b/boards/waveshare/rp2040_plus/rp2040_plus_16mb_defconfig
new file mode 100644
index 0000000000000..ec7e8e3f93178
--- /dev/null
+++ b/boards/waveshare/rp2040_plus/rp2040_plus_16mb_defconfig
@@ -0,0 +1,12 @@
+# SPDX-License-Identifier: Apache-2.0
+
+CONFIG_SERIAL=y
+CONFIG_CONSOLE=y
+CONFIG_UART_CONSOLE=y
+CONFIG_GPIO=y
+CONFIG_USE_DT_CODE_PARTITION=y
+CONFIG_BUILD_OUTPUT_UF2=y
+CONFIG_BUILD_OUTPUT_HEX=y
+CONFIG_UART_INTERRUPT_DRIVEN=y
+CONFIG_RESET=y
+CONFIG_CLOCK_CONTROL=y