diff --git a/CHANGELOG.md b/CHANGELOG.md
index c42dbd18a76a..2be85bf37b81 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -16,6 +16,7 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 - Use local user CSS cache for `@apply` ([#7524](https://github.com/tailwindlabs/tailwindcss/pull/7524))
 - Invalidate context when main CSS changes ([#7626](https://github.com/tailwindlabs/tailwindcss/pull/7626))
 - Only add `!` to selector class matching template candidate when using important modifier with mutli-class selectors ([#7664](https://github.com/tailwindlabs/tailwindcss/pull/7664))
+- Correctly parse and prefix animation names with dots ([#7163](https://github.com/tailwindlabs/tailwindcss/pull/7163))
 
 ### Changed
 
diff --git a/src/corePlugins.js b/src/corePlugins.js
index b9b9a340363a..ced2be2163e5 100644
--- a/src/corePlugins.js
+++ b/src/corePlugins.js
@@ -3,6 +3,7 @@ import * as path from 'path'
 import postcss from 'postcss'
 import createUtilityPlugin from './util/createUtilityPlugin'
 import buildMediaQuery from './util/buildMediaQuery'
+import escapeClassName from './util/escapeClassName'
 import parseAnimationValue from './util/parseAnimationValue'
 import flattenColorPalette from './util/flattenColorPalette'
 import withAlphaVariable, { withAlphaValue } from './util/withAlphaVariable'
@@ -612,8 +613,8 @@ export let corePlugins = {
     })
   },
 
-  animation: ({ matchUtilities, theme, prefix }) => {
-    let prefixName = (name) => prefix(`.${name}`).slice(1)
+  animation: ({ matchUtilities, theme, config }) => {
+    let prefixName = (name) => `${config('prefix')}${escapeClassName(name)}`
     let keyframes = Object.fromEntries(
       Object.entries(theme('keyframes') ?? {}).map(([key, value]) => {
         return [key, { [`@keyframes ${prefixName(key)}`]: value }]
diff --git a/tests/animations.test.js b/tests/animations.test.js
index 0a77a4c4e415..a1c580a79bd3 100644
--- a/tests/animations.test.js
+++ b/tests/animations.test.js
@@ -181,3 +181,96 @@ test('multiple custom', () => {
     `)
   })
 })
+
+test('with dots in the name', () => {
+  let config = {
+    content: [
+      {
+        raw: html`
+          <div class="animate-zoom-.5"></div>
+          <div class="animate-zoom-1.5"></div>
+        `,
+      },
+    ],
+    theme: {
+      extend: {
+        keyframes: {
+          'zoom-.5': { to: { transform: 'scale(0.5)' } },
+          'zoom-1.5': { to: { transform: 'scale(1.5)' } },
+        },
+        animation: {
+          'zoom-.5': 'zoom-.5 2s',
+          'zoom-1.5': 'zoom-1.5 2s',
+        },
+      },
+    },
+  }
+
+  return run('@tailwind utilities', config).then((result) => {
+    expect(result.css).toMatchFormattedCss(css`
+      @keyframes zoom-\.5 {
+        to {
+          transform: scale(0.5);
+        }
+      }
+      .animate-zoom-\.5 {
+        animation: zoom-\.5 2s;
+      }
+      @keyframes zoom-1\.5 {
+        to {
+          transform: scale(1.5);
+        }
+      }
+      .animate-zoom-1\.5 {
+        animation: zoom-1\.5 2s;
+      }
+    `)
+  })
+})
+
+test('with dots in the name and prefix', () => {
+  let config = {
+    prefix: 'tw-',
+    content: [
+      {
+        raw: html`
+          <div class="tw-animate-zoom-.5"></div>
+          <div class="tw-animate-zoom-1.5"></div>
+        `,
+      },
+    ],
+    theme: {
+      extend: {
+        keyframes: {
+          'zoom-.5': { to: { transform: 'scale(0.5)' } },
+          'zoom-1.5': { to: { transform: 'scale(1.5)' } },
+        },
+        animation: {
+          'zoom-.5': 'zoom-.5 2s',
+          'zoom-1.5': 'zoom-1.5 2s',
+        },
+      },
+    },
+  }
+
+  return run('@tailwind utilities', config).then((result) => {
+    expect(result.css).toMatchFormattedCss(css`
+      @keyframes tw-zoom-\.5 {
+        to {
+          transform: scale(0.5);
+        }
+      }
+      .tw-animate-zoom-\.5 {
+        animation: tw-zoom-\.5 2s;
+      }
+      @keyframes tw-zoom-1\.5 {
+        to {
+          transform: scale(1.5);
+        }
+      }
+      .tw-animate-zoom-1\.5 {
+        animation: tw-zoom-1\.5 2s;
+      }
+    `)
+  })
+})