diff --git a/Python/bytecodes.c b/Python/bytecodes.c
index 9a1af0e920188b..33a242fe068777 100644
--- a/Python/bytecodes.c
+++ b/Python/bytecodes.c
@@ -1182,7 +1182,6 @@ dummy_func(
                     assert(!_PyErr_Occurred(tstate));
                 }
                 else {
-                    assert(PyLong_Check(lasti));
                     _PyErr_SetString(tstate, PyExc_SystemError, "lasti is not an int");
                     ERROR_NO_POP();
                 }
diff --git a/Python/generated_cases.c.h b/Python/generated_cases.c.h
index f670353cdbde56..ac09b83fd2a2ec 100644
--- a/Python/generated_cases.c.h
+++ b/Python/generated_cases.c.h
@@ -5875,7 +5875,6 @@
                     assert(!_PyErr_Occurred(tstate));
                 }
                 else {
-                    assert(PyLong_Check(lasti));
                     _PyErr_SetString(tstate, PyExc_SystemError, "lasti is not an int");
                     goto error;
                 }