diff --git a/.changeset/warm-sloths-tickle.md b/.changeset/warm-sloths-tickle.md
new file mode 100644
index 00000000000..1a300487110
--- /dev/null
+++ b/.changeset/warm-sloths-tickle.md
@@ -0,0 +1,5 @@
+---
+'@primer/react': patch
+---
+
+Update the resize behavior of PageLayout to ignore right clicks when resizing
diff --git a/src/PageLayout/PageLayout.tsx b/src/PageLayout/PageLayout.tsx
index 378d8fe8c3d..7b18f7bf0b4 100644
--- a/src/PageLayout/PageLayout.tsx
+++ b/src/PageLayout/PageLayout.tsx
@@ -352,9 +352,11 @@ const VerticalDivider: React.FC<React.PropsWithChildren<DividerProps & Draggable
             aria-valuenow={currentWidth}
             aria-valuetext={`Pane width ${currentWidth} pixels`}
             tabIndex={0}
-            onMouseDown={() => {
-              setIsDragging(true)
-              onDragStart?.()
+            onMouseDown={event => {
+              if (event.button === 0) {
+                setIsDragging(true)
+                onDragStart?.()
+              }
             }}
             onKeyDown={event => {
               if (