diff --git a/Cargo.lock b/Cargo.lock
index 367713b9361ba..8216b8b92aef5 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -593,9 +593,9 @@ dependencies = [
 
 [[package]]
 name = "blake2"
-version = "0.10.2"
+version = "0.10.4"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "b94ba84325db59637ffc528bbe8c7f86c02c57cff5c0e2b9b00f9a851f42f309"
+checksum = "b9cf849ee05b2ee5fba5e36f97ff8ec2533916700fc0758d40d92136a42f3388"
 dependencies = [
  "digest 0.10.3",
 ]
@@ -9751,7 +9751,7 @@ version = "6.0.0"
 dependencies = [
  "base58",
  "bitflags",
- "blake2-rfc",
+ "blake2",
  "byteorder",
  "criterion",
  "dyn-clonable",
diff --git a/primitives/api/proc-macro/Cargo.toml b/primitives/api/proc-macro/Cargo.toml
index 0a57be8d7a300..8acc15d6a0591 100644
--- a/primitives/api/proc-macro/Cargo.toml
+++ b/primitives/api/proc-macro/Cargo.toml
@@ -19,7 +19,7 @@ proc-macro = true
 quote = "1.0.10"
 syn = { version = "1.0.98", features = ["full", "fold", "extra-traits", "visit"] }
 proc-macro2 = "1.0.37"
-blake2 = { version = "0.10.2", default-features = false }
+blake2 = { version = "0.10.4", default-features = false }
 proc-macro-crate = "1.1.3"
 
 # Required for the doc tests
diff --git a/primitives/core/Cargo.toml b/primitives/core/Cargo.toml
index b611449b6730f..2233a3443447c 100644
--- a/primitives/core/Cargo.toml
+++ b/primitives/core/Cargo.toml
@@ -48,7 +48,7 @@ bitflags = "1.3"
 
 # full crypto
 ed25519-zebra = { version = "3.0.0", default-features = false, optional = true}
-blake2-rfc = { version = "0.2.18", default-features = false, optional = true }
+blake2 = { version = "0.10.4", default-features = false, optional = true }
 schnorrkel = { version = "0.9.1", features = [
 	"preaudit_deprecated",
 	"u64_backend",
@@ -98,7 +98,7 @@ std = [
 	"hash-db/std",
 	"sp-std/std",
 	"serde",
-	"blake2-rfc/std",
+	"blake2/std",
 	"ed25519-zebra",
 	"hex/std",
 	"base58",
@@ -130,7 +130,7 @@ std = [
 # For the regular wasm runtime builds this should not be used.
 full_crypto = [
 	"ed25519-zebra",
-	"blake2-rfc",
+	"blake2",
 	"schnorrkel",
 	"hex",
 	"libsecp256k1",
diff --git a/primitives/core/hashing/Cargo.toml b/primitives/core/hashing/Cargo.toml
index d6fc6bed31fec..efe38af1602dd 100644
--- a/primitives/core/hashing/Cargo.toml
+++ b/primitives/core/hashing/Cargo.toml
@@ -13,7 +13,7 @@ documentation = "https://docs.rs/sp-core-hashing"
 targets = ["x86_64-unknown-linux-gnu"]
 
 [dependencies]
-blake2 = { version = "0.10.2", default-features = false }
+blake2 = { version = "0.10.4", default-features = false }
 byteorder = { version = "1.3.2", default-features = false }
 digest = { version = "0.10.3", default-features = false }
 sha2 = { version = "0.10.2", default-features = false }
diff --git a/primitives/core/src/crypto.rs b/primitives/core/src/crypto.rs
index 80b44449dbac1..377ae480edd17 100644
--- a/primitives/core/src/crypto.rs
+++ b/primitives/core/src/crypto.rs
@@ -132,9 +132,7 @@ impl DeriveJunction {
 		let mut cc: [u8; JUNCTION_ID_LEN] = Default::default();
 		index.using_encoded(|data| {
 			if data.len() > JUNCTION_ID_LEN {
-				let hash_result = blake2_rfc::blake2b::blake2b(JUNCTION_ID_LEN, &[], data);
-				let hash = hash_result.as_bytes();
-				cc.copy_from_slice(hash);
+				cc.copy_from_slice(&sp_core_hashing::blake2_256(data));
 			} else {
 				cc[0..data.len()].copy_from_slice(data);
 			}
@@ -292,7 +290,7 @@ pub trait Ss58Codec: Sized + AsMut<[u8]> + AsRef<[u8]> + ByteArray {
 		}
 
 		let hash = ss58hash(&data[0..body_len + prefix_len]);
-		let checksum = &hash.as_bytes()[0..CHECKSUM_LEN];
+		let checksum = &hash[0..CHECKSUM_LEN];
 		if data[body_len + prefix_len..body_len + prefix_len + CHECKSUM_LEN] != *checksum {
 			// Invalid checksum.
 			return Err(PublicError::InvalidChecksum)
@@ -333,7 +331,7 @@ pub trait Ss58Codec: Sized + AsMut<[u8]> + AsRef<[u8]> + ByteArray {
 		};
 		v.extend(self.as_ref());
 		let r = ss58hash(&v);
-		v.extend(&r.as_bytes()[0..2]);
+		v.extend(&r[0..2]);
 		v.to_base58()
 	}
 
@@ -366,11 +364,13 @@ pub trait Derive: Sized {
 const PREFIX: &[u8] = b"SS58PRE";
 
 #[cfg(feature = "std")]
-fn ss58hash(data: &[u8]) -> blake2_rfc::blake2b::Blake2bResult {
-	let mut context = blake2_rfc::blake2b::Blake2b::new(64);
-	context.update(PREFIX);
-	context.update(data);
-	context.finalize()
+fn ss58hash(data: &[u8]) -> Vec<u8> {
+	use blake2::{Blake2b512, Digest};
+
+	let mut ctx = Blake2b512::new();
+	ctx.update(PREFIX);
+	ctx.update(data);
+	ctx.finalize().to_vec()
 }
 
 /// Default prefix number
@@ -1311,6 +1311,14 @@ mod tests {
 				path: vec![DeriveJunction::soft("DOT")]
 			})
 		);
+		assert_eq!(
+			TestPair::from_string("hello world/0123456789012345678901234567890123456789", None),
+			Ok(TestPair::Standard {
+				phrase: "hello world".to_owned(),
+				password: None,
+				path: vec![DeriveJunction::soft("0123456789012345678901234567890123456789")]
+			})
+		);
 		assert_eq!(
 			TestPair::from_string("hello world//1", None),
 			Ok(TestPair::Standard {
@@ -1327,6 +1335,14 @@ mod tests {
 				path: vec![DeriveJunction::hard("DOT")]
 			})
 		);
+		assert_eq!(
+			TestPair::from_string("hello world//0123456789012345678901234567890123456789", None),
+			Ok(TestPair::Standard {
+				phrase: "hello world".to_owned(),
+				password: None,
+				path: vec![DeriveJunction::hard("0123456789012345678901234567890123456789")]
+			})
+		);
 		assert_eq!(
 			TestPair::from_string("hello world//1/DOT", None),
 			Ok(TestPair::Standard {