diff --git a/app/code/Magento/Integration/Setup/UpgradeSchema.php b/app/code/Magento/Integration/Setup/UpgradeSchema.php
index 6173a359329b0..21aea4e4122c9 100644
--- a/app/code/Magento/Integration/Setup/UpgradeSchema.php
+++ b/app/code/Magento/Integration/Setup/UpgradeSchema.php
@@ -71,6 +71,16 @@ public function upgrade(SchemaSetupInterface $setup, ModuleContextInterface $con
             $setup->getConnection()->createTable($table);
         }
 
+        if (version_compare($context->getVersion(), '2.2.1', '<')) {
+            $connection = $setup->getConnection();
+
+            $connection->addIndex(
+                $setup->getTable('oauth_nonce'),
+                $setup->getIdxName('oauth_nonce', ['timestamp']),
+                ['timestamp']
+            );
+        }
+
         $setup->endSetup();
     }
 }
diff --git a/app/code/Magento/Integration/etc/module.xml b/app/code/Magento/Integration/etc/module.xml
index c5e2aa75a8d05..d62b00ae8e3f3 100644
--- a/app/code/Magento/Integration/etc/module.xml
+++ b/app/code/Magento/Integration/etc/module.xml
@@ -6,7 +6,7 @@
  */
 -->
 <config xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:noNamespaceSchemaLocation="urn:magento:framework:Module/etc/module.xsd">
-    <module name="Magento_Integration" setup_version="2.2.0">
+    <module name="Magento_Integration" setup_version="2.2.1">
         <sequence>
             <module name="Magento_Store"/>
             <module name="Magento_User"/>