AVX512IFMA/AVXIFMA targets should be able to fold vXi64 mul-add patterns assuming the multiplicands are known to be u52 integers
X86ISD::VPMADD52L patterns can be matched for (X * Y) + Z if the upper 12 bits of X, Y AND (X * Y) are all known zero
X86ISD::VPMADD52H patterns are trickier as we extract the upper 52 bits of the (X * Y) 104-bit mulu extended result, but at least basic matching might be achievable