diff --git a/packages/browser/src/integrations/breadcrumbs.ts b/packages/browser/src/integrations/breadcrumbs.ts
index 0fb305767414..efef3f8057cd 100644
--- a/packages/browser/src/integrations/breadcrumbs.ts
+++ b/packages/browser/src/integrations/breadcrumbs.ts
@@ -70,8 +70,6 @@ const _breadcrumbsIntegration = ((options: Partial<BreadcrumbsOptions> = {}) =>
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     setup(client) {
       if (_options.console) {
         addConsoleInstrumentationHandler(_getConsoleBreadcrumbHandler(client));
diff --git a/packages/browser/src/integrations/dedupe.ts b/packages/browser/src/integrations/dedupe.ts
index f4ace6011b19..1e12b5c5a92c 100644
--- a/packages/browser/src/integrations/dedupe.ts
+++ b/packages/browser/src/integrations/dedupe.ts
@@ -11,8 +11,6 @@ const _dedupeIntegration = (() => {
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     processEvent(currentEvent) {
       // We want to ignore any non-error type events, e.g. transactions or replays
       // These should never be deduped, and also not be compared against as _previousEvent.
diff --git a/packages/browser/src/integrations/httpcontext.ts b/packages/browser/src/integrations/httpcontext.ts
index 1a5e95f2eee3..5fa59dd3585d 100644
--- a/packages/browser/src/integrations/httpcontext.ts
+++ b/packages/browser/src/integrations/httpcontext.ts
@@ -8,8 +8,6 @@ const INTEGRATION_NAME = 'HttpContext';
 const _httpContextIntegration = (() => {
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     preprocessEvent(event) {
       // if none of the information we want exists, don't bother
       if (!WINDOW.navigator && !WINDOW.location && !WINDOW.document) {
diff --git a/packages/browser/src/integrations/linkederrors.ts b/packages/browser/src/integrations/linkederrors.ts
index b03855303c58..8d15b2055048 100644
--- a/packages/browser/src/integrations/linkederrors.ts
+++ b/packages/browser/src/integrations/linkederrors.ts
@@ -19,8 +19,6 @@ const _linkedErrorsIntegration = ((options: LinkedErrorsOptions = {}) => {
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     preprocessEvent(event, hint, client) {
       const options = client.getOptions();
 
diff --git a/packages/browser/src/profiling/integration.ts b/packages/browser/src/profiling/integration.ts
index 1c076e09b17d..f9b924d9102c 100644
--- a/packages/browser/src/profiling/integration.ts
+++ b/packages/browser/src/profiling/integration.ts
@@ -22,7 +22,6 @@ const _browserProfilingIntegration = (() => {
   return {
     name: INTEGRATION_NAME,
     // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     setup(client) {
       const scope = getCurrentScope();
 
diff --git a/packages/core/src/integration.ts b/packages/core/src/integration.ts
index 1e0273d72f2b..ccf1f86cff18 100644
--- a/packages/core/src/integration.ts
+++ b/packages/core/src/integration.ts
@@ -129,7 +129,7 @@ export function setupIntegration(client: Client, integration: Integration, integ
   integrationIndex[integration.name] = integration;
 
   // `setupOnce` is only called the first time
-  if (installedIntegrations.indexOf(integration.name) === -1) {
+  if (installedIntegrations.indexOf(integration.name) === -1 && typeof integration.setupOnce === 'function') {
     // eslint-disable-next-line deprecation/deprecation
     integration.setupOnce(addGlobalEventProcessor, getCurrentHub);
     installedIntegrations.push(integration.name);
diff --git a/packages/core/src/integrations/inboundfilters.ts b/packages/core/src/integrations/inboundfilters.ts
index 6ed891c253fa..dff1130cb708 100644
--- a/packages/core/src/integrations/inboundfilters.ts
+++ b/packages/core/src/integrations/inboundfilters.ts
@@ -33,8 +33,6 @@ const INTEGRATION_NAME = 'InboundFilters';
 const _inboundFiltersIntegration = ((options: Partial<InboundFiltersOptions> = {}) => {
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     processEvent(event, _hint, client) {
       const clientOptions = client.getOptions();
       const mergedOptions = _mergeOptions(options, clientOptions);
diff --git a/packages/core/src/integrations/linkederrors.ts b/packages/core/src/integrations/linkederrors.ts
index e753ca2ccd75..b23eaf4272b0 100644
--- a/packages/core/src/integrations/linkederrors.ts
+++ b/packages/core/src/integrations/linkederrors.ts
@@ -18,8 +18,6 @@ const _linkedErrorsIntegration = ((options: LinkedErrorsOptions = {}) => {
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     preprocessEvent(event, hint, client) {
       const options = client.getOptions();
 
diff --git a/packages/core/src/integrations/metadata.ts b/packages/core/src/integrations/metadata.ts
index 3d5b89e07d2e..99fc4834b060 100644
--- a/packages/core/src/integrations/metadata.ts
+++ b/packages/core/src/integrations/metadata.ts
@@ -9,8 +9,6 @@ const INTEGRATION_NAME = 'ModuleMetadata';
 const _moduleMetadataIntegration = (() => {
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     setup(client) {
       // We need to strip metadata from stack frames before sending them to Sentry since these are client side only.
       client.on('beforeEnvelope', envelope => {
diff --git a/packages/core/src/integrations/requestdata.ts b/packages/core/src/integrations/requestdata.ts
index 1835fda4ec4a..002673cdc13f 100644
--- a/packages/core/src/integrations/requestdata.ts
+++ b/packages/core/src/integrations/requestdata.ts
@@ -75,8 +75,6 @@ const _requestDataIntegration = ((options: RequestDataIntegrationOptions = {}) =
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     processEvent(event, _hint, client) {
       // Note: In the long run, most of the logic here should probably move into the request data utility functions. For
       // the moment it lives here, though, until https://github.com/getsentry/sentry-javascript/issues/5718 is addressed.
diff --git a/packages/deno/src/integrations/context.ts b/packages/deno/src/integrations/context.ts
index f844b80be6c8..ca0735c4e0ab 100644
--- a/packages/deno/src/integrations/context.ts
+++ b/packages/deno/src/integrations/context.ts
@@ -55,8 +55,6 @@ async function addDenoRuntimeContext(event: Event): Promise<Event> {
 const _denoContextIntegration = (() => {
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     processEvent(event) {
       return addDenoRuntimeContext(event);
     },
diff --git a/packages/deno/src/integrations/contextlines.ts b/packages/deno/src/integrations/contextlines.ts
index fc51e4ad2d57..4b43c6bc34c2 100644
--- a/packages/deno/src/integrations/contextlines.ts
+++ b/packages/deno/src/integrations/contextlines.ts
@@ -52,8 +52,6 @@ const _contextLinesIntegration = ((options: ContextLinesOptions = {}) => {
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     processEvent(event) {
       return addSourceContext(event, contextLines);
     },
diff --git a/packages/deno/src/integrations/globalhandlers.ts b/packages/deno/src/integrations/globalhandlers.ts
index 2c562a7aa0f9..6498f2e2ffb5 100644
--- a/packages/deno/src/integrations/globalhandlers.ts
+++ b/packages/deno/src/integrations/globalhandlers.ts
@@ -31,8 +31,6 @@ const _globalHandlersIntegration = ((options?: GlobalHandlersIntegrations) => {
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     setup(client) {
       if (_options.error) {
         installGlobalErrorHandler(client);
diff --git a/packages/deno/src/integrations/normalizepaths.ts b/packages/deno/src/integrations/normalizepaths.ts
index a9b8f3dbb0e3..d5304e9e62dd 100644
--- a/packages/deno/src/integrations/normalizepaths.ts
+++ b/packages/deno/src/integrations/normalizepaths.ts
@@ -70,8 +70,6 @@ const _normalizePathsIntegration = (() => {
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     processEvent(event) {
       // This error.stack hopefully contains paths that traverse the app cwd
       const error = new Error();
diff --git a/packages/integrations/src/captureconsole.ts b/packages/integrations/src/captureconsole.ts
index 43419dcd32bd..2593ec8de7f2 100644
--- a/packages/integrations/src/captureconsole.ts
+++ b/packages/integrations/src/captureconsole.ts
@@ -20,8 +20,6 @@ const _captureConsoleIntegration = ((options: CaptureConsoleOptions = {}) => {
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     setup(client) {
       if (!('console' in GLOBAL_OBJ)) {
         return;
diff --git a/packages/integrations/src/contextlines.ts b/packages/integrations/src/contextlines.ts
index 62c1b2728f1a..8e77ea6f8a08 100644
--- a/packages/integrations/src/contextlines.ts
+++ b/packages/integrations/src/contextlines.ts
@@ -23,8 +23,6 @@ const _contextLinesIntegration = ((options: ContextLinesOptions = {}) => {
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     processEvent(event) {
       return addSourceContext(event, contextLines);
     },
diff --git a/packages/integrations/src/debug.ts b/packages/integrations/src/debug.ts
index 1c1911cd03d8..559041b40d36 100644
--- a/packages/integrations/src/debug.ts
+++ b/packages/integrations/src/debug.ts
@@ -24,8 +24,6 @@ const _debugIntegration = ((options: DebugOptions = {}) => {
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     setup(client) {
       client.on('beforeSendEvent', (event: Event, hint?: EventHint) => {
         if (_options.debugger) {
diff --git a/packages/integrations/src/dedupe.ts b/packages/integrations/src/dedupe.ts
index 63db131127c9..5aeafd42e97e 100644
--- a/packages/integrations/src/dedupe.ts
+++ b/packages/integrations/src/dedupe.ts
@@ -11,8 +11,6 @@ const _dedupeIntegration = (() => {
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     processEvent(currentEvent) {
       // We want to ignore any non-error type events, e.g. transactions or replays
       // These should never be deduped, and also not be compared against as _previousEvent.
diff --git a/packages/integrations/src/extraerrordata.ts b/packages/integrations/src/extraerrordata.ts
index 21cc91008b7f..fc0c9c05fe58 100644
--- a/packages/integrations/src/extraerrordata.ts
+++ b/packages/integrations/src/extraerrordata.ts
@@ -27,8 +27,6 @@ const _extraErrorDataIntegration = ((options: Partial<ExtraErrorDataOptions> = {
   const { depth = 3, captureErrorCause = true } = options;
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     processEvent(event, hint) {
       return _enhanceEventWithErrorData(event, hint, depth, captureErrorCause);
     },
diff --git a/packages/integrations/src/httpclient.ts b/packages/integrations/src/httpclient.ts
index 276aadaf9baa..1c93a232104b 100644
--- a/packages/integrations/src/httpclient.ts
+++ b/packages/integrations/src/httpclient.ts
@@ -47,8 +47,6 @@ const _httpClientIntegration = ((options: Partial<HttpClientOptions> = {}) => {
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     setup(client): void {
       _wrapFetch(client, _options);
       _wrapXHR(client, _options);
diff --git a/packages/integrations/src/rewriteframes.ts b/packages/integrations/src/rewriteframes.ts
index 12183a3192ae..d32252ef15d8 100644
--- a/packages/integrations/src/rewriteframes.ts
+++ b/packages/integrations/src/rewriteframes.ts
@@ -71,8 +71,6 @@ const _rewriteFramesIntegration = ((options: RewriteFramesOptions = {}) => {
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     processEvent(originalEvent) {
       let processedEvent = originalEvent;
 
diff --git a/packages/integrations/src/sessiontiming.ts b/packages/integrations/src/sessiontiming.ts
index 2c79dd5cd69a..41af19bed15c 100644
--- a/packages/integrations/src/sessiontiming.ts
+++ b/packages/integrations/src/sessiontiming.ts
@@ -8,8 +8,6 @@ const _sessionTimingIntegration = (() => {
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     processEvent(event) {
       const now = Date.now();
 
diff --git a/packages/integrations/test/reportingobserver.test.ts b/packages/integrations/test/reportingobserver.test.ts
index 8c8088770973..a8766e7cd58c 100644
--- a/packages/integrations/test/reportingobserver.test.ts
+++ b/packages/integrations/test/reportingobserver.test.ts
@@ -50,7 +50,7 @@ describe('ReportingObserver', () => {
       const reportingObserver = reportingObserverIntegration();
 
       expect(() => {
-        reportingObserver.setupOnce();
+        reportingObserver.setupOnce!();
       }).not.toThrow();
 
       expect(mockReportingObserverConstructor).not.toHaveBeenCalled();
@@ -59,7 +59,7 @@ describe('ReportingObserver', () => {
 
     it('should use default report types', () => {
       const reportingObserver = reportingObserverIntegration();
-      reportingObserver.setupOnce();
+      reportingObserver.setupOnce!();
       reportingObserver.setup?.(mockClient);
 
       expect(mockReportingObserverConstructor).toHaveBeenCalledTimes(1);
@@ -71,7 +71,7 @@ describe('ReportingObserver', () => {
 
     it('should use user-provided report types', () => {
       const reportingObserver = reportingObserverIntegration({ types: ['crash'] });
-      reportingObserver.setupOnce();
+      reportingObserver.setupOnce!();
       reportingObserver.setup?.(mockClient);
 
       expect(mockReportingObserverConstructor).toHaveBeenCalledTimes(1);
@@ -83,7 +83,7 @@ describe('ReportingObserver', () => {
 
     it('should use `buffered` option', () => {
       const reportingObserver = reportingObserverIntegration();
-      reportingObserver.setupOnce();
+      reportingObserver.setupOnce!();
       reportingObserver.setup?.(mockClient);
 
       expect(mockReportingObserverConstructor).toHaveBeenCalledTimes(1);
@@ -95,7 +95,7 @@ describe('ReportingObserver', () => {
 
     it('should call `observe` function', () => {
       const reportingObserver = reportingObserverIntegration();
-      reportingObserver.setupOnce();
+      reportingObserver.setupOnce!();
       reportingObserver.setup?.(mockClient);
 
       expect(mockObserve).toHaveBeenCalledTimes(1);
@@ -105,7 +105,7 @@ describe('ReportingObserver', () => {
   describe('handler', () => {
     it('should abort gracefully and not do anything when integration is not installed', () => {
       const reportingObserver = reportingObserverIntegration();
-      reportingObserver.setupOnce();
+      reportingObserver.setupOnce!();
       // without calling setup, the integration is not registered
 
       const handler = mockReportingObserverConstructor.mock.calls[0][0];
@@ -119,7 +119,7 @@ describe('ReportingObserver', () => {
 
     it('should capture messages', () => {
       const reportingObserver = reportingObserverIntegration();
-      reportingObserver.setupOnce();
+      reportingObserver.setupOnce!();
       reportingObserver.setup?.(mockClient);
       const handler = mockReportingObserverConstructor.mock.calls[0][0];
 
@@ -133,7 +133,7 @@ describe('ReportingObserver', () => {
 
     it('should set extra including the url of a report', () => {
       const reportingObserver = reportingObserverIntegration();
-      reportingObserver.setupOnce();
+      reportingObserver.setupOnce!();
       reportingObserver.setup?.(mockClient);
       const handler = mockReportingObserverConstructor.mock.calls[0][0];
 
@@ -148,7 +148,7 @@ describe('ReportingObserver', () => {
 
     it('should set extra including the report body if available', () => {
       const reportingObserver = reportingObserverIntegration();
-      reportingObserver.setupOnce();
+      reportingObserver.setupOnce!();
       reportingObserver.setup?.(mockClient);
       const handler = mockReportingObserverConstructor.mock.calls[0][0];
 
@@ -163,7 +163,7 @@ describe('ReportingObserver', () => {
 
     it('should not set extra report body extra when no body is set', () => {
       const reportingObserver = reportingObserverIntegration();
-      reportingObserver.setupOnce();
+      reportingObserver.setupOnce!();
       reportingObserver.setup?.(mockClient);
       const handler = mockReportingObserverConstructor.mock.calls[0][0];
 
@@ -174,7 +174,7 @@ describe('ReportingObserver', () => {
 
     it('should capture report details from body on crash report', () => {
       const reportingObserver = reportingObserverIntegration();
-      reportingObserver.setupOnce();
+      reportingObserver.setupOnce!();
       reportingObserver.setup?.(mockClient);
       const handler = mockReportingObserverConstructor.mock.calls[0][0];
 
@@ -192,7 +192,7 @@ describe('ReportingObserver', () => {
 
     it('should capture report message from body on deprecation report', () => {
       const reportingObserver = reportingObserverIntegration();
-      reportingObserver.setupOnce();
+      reportingObserver.setupOnce!();
       reportingObserver.setup?.(mockClient);
       const handler = mockReportingObserverConstructor.mock.calls[0][0];
 
@@ -209,7 +209,7 @@ describe('ReportingObserver', () => {
 
     it('should capture report message from body on intervention report', () => {
       const reportingObserver = reportingObserverIntegration();
-      reportingObserver.setupOnce();
+      reportingObserver.setupOnce!();
       reportingObserver.setup?.(mockClient);
       const handler = mockReportingObserverConstructor.mock.calls[0][0];
 
@@ -226,7 +226,7 @@ describe('ReportingObserver', () => {
 
     it('should use fallback message when no body is available', () => {
       const reportingObserver = reportingObserverIntegration();
-      reportingObserver.setupOnce();
+      reportingObserver.setupOnce!();
       reportingObserver.setup?.(mockClient);
       const handler = mockReportingObserverConstructor.mock.calls[0][0];
 
@@ -242,7 +242,7 @@ describe('ReportingObserver', () => {
 
     it('should use fallback message when no body details are available for crash report', () => {
       const reportingObserver = reportingObserverIntegration();
-      reportingObserver.setupOnce();
+      reportingObserver.setupOnce!();
       reportingObserver.setup?.(mockClient);
       const handler = mockReportingObserverConstructor.mock.calls[0][0];
 
@@ -255,7 +255,7 @@ describe('ReportingObserver', () => {
 
     it('should use fallback message when no body message is available for deprecation report', () => {
       const reportingObserver = reportingObserverIntegration();
-      reportingObserver.setupOnce();
+      reportingObserver.setupOnce!();
       reportingObserver.setup?.(mockClient);
       const handler = mockReportingObserverConstructor.mock.calls[0][0];
 
@@ -272,7 +272,7 @@ describe('ReportingObserver', () => {
 
     it('should use fallback message when no body message is available for intervention report', () => {
       const reportingObserver = reportingObserverIntegration();
-      reportingObserver.setupOnce();
+      reportingObserver.setupOnce!();
       reportingObserver.setup?.(mockClient);
       const handler = mockReportingObserverConstructor.mock.calls[0][0];
 
diff --git a/packages/node/src/integrations/anr/index.ts b/packages/node/src/integrations/anr/index.ts
index 7da63fdc50bd..bfb81557fd75 100644
--- a/packages/node/src/integrations/anr/index.ts
+++ b/packages/node/src/integrations/anr/index.ts
@@ -55,8 +55,6 @@ const INTEGRATION_NAME = 'Anr';
 const _anrIntegration = ((options: Partial<AnrIntegrationOptions> = {}) => {
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     setup(client: NodeClient) {
       if (NODE_VERSION.major < 16 || (NODE_VERSION.major === 16 && NODE_VERSION.minor < 17)) {
         throw new Error('ANR detection requires Node 16.17.0 or later');
diff --git a/packages/node/src/integrations/console.ts b/packages/node/src/integrations/console.ts
index aacf3447ea2a..5a185b8fcee1 100644
--- a/packages/node/src/integrations/console.ts
+++ b/packages/node/src/integrations/console.ts
@@ -8,8 +8,6 @@ const INTEGRATION_NAME = 'Console';
 const _consoleIntegration = (() => {
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     setup(client) {
       addConsoleInstrumentationHandler(({ args, level }) => {
         if (getClient() !== client) {
diff --git a/packages/node/src/integrations/context.ts b/packages/node/src/integrations/context.ts
index db712f4ea95d..fa5184204bf2 100644
--- a/packages/node/src/integrations/context.ts
+++ b/packages/node/src/integrations/context.ts
@@ -102,8 +102,6 @@ const _nodeContextIntegration = ((options: ContextOptions = {}) => {
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     processEvent(event) {
       return addContext(event);
     },
diff --git a/packages/node/src/integrations/contextlines.ts b/packages/node/src/integrations/contextlines.ts
index 5e98c7cbb813..2f292a5606dc 100644
--- a/packages/node/src/integrations/contextlines.ts
+++ b/packages/node/src/integrations/contextlines.ts
@@ -40,8 +40,6 @@ const _contextLinesIntegration = ((options: ContextLinesOptions = {}) => {
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     processEvent(event) {
       return addSourceContext(event, contextLines);
     },
diff --git a/packages/node/src/integrations/local-variables/local-variables-async.ts b/packages/node/src/integrations/local-variables/local-variables-async.ts
index b5f015b2b7db..0d04f1f0b6e1 100644
--- a/packages/node/src/integrations/local-variables/local-variables-async.ts
+++ b/packages/node/src/integrations/local-variables/local-variables-async.ts
@@ -220,8 +220,6 @@ const _localVariablesAsyncIntegration = ((options: LocalVariablesIntegrationOpti
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     setup(client: NodeClient) {
       const clientOptions = client.getOptions();
 
diff --git a/packages/node/src/integrations/modules.ts b/packages/node/src/integrations/modules.ts
index 008376670724..1f9aff7303e3 100644
--- a/packages/node/src/integrations/modules.ts
+++ b/packages/node/src/integrations/modules.ts
@@ -79,8 +79,6 @@ function _getModules(): { [key: string]: string } {
 const _modulesIntegration = (() => {
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     processEvent(event) {
       event.modules = {
         ...event.modules,
diff --git a/packages/node/src/integrations/onuncaughtexception.ts b/packages/node/src/integrations/onuncaughtexception.ts
index 0eb79833ddbf..68be68a6d6cc 100644
--- a/packages/node/src/integrations/onuncaughtexception.ts
+++ b/packages/node/src/integrations/onuncaughtexception.ts
@@ -48,8 +48,6 @@ const _onUncaughtExceptionIntegration = ((options: Partial<OnUncaughtExceptionOp
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     setup(client: NodeClient) {
       global.process.on('uncaughtException', makeErrorHandler(client, _options));
     },
diff --git a/packages/node/src/integrations/onunhandledrejection.ts b/packages/node/src/integrations/onunhandledrejection.ts
index 0c44c0e983c0..9f3801b7a0cf 100644
--- a/packages/node/src/integrations/onunhandledrejection.ts
+++ b/packages/node/src/integrations/onunhandledrejection.ts
@@ -21,8 +21,6 @@ const _onUnhandledRejectionIntegration = ((options: Partial<OnUnhandledRejection
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     setup(client) {
       global.process.on('unhandledRejection', makeUnhandledPromiseHandler(client, { mode }));
     },
diff --git a/packages/node/src/integrations/spotlight.ts b/packages/node/src/integrations/spotlight.ts
index bf72f653f58c..eb9c34260b61 100644
--- a/packages/node/src/integrations/spotlight.ts
+++ b/packages/node/src/integrations/spotlight.ts
@@ -21,8 +21,6 @@ const _spotlightIntegration = ((options: Partial<SpotlightConnectionOptions> = {
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     setup(client) {
       if (typeof process === 'object' && process.env && process.env.NODE_ENV !== 'development') {
         logger.warn("[Spotlight] It seems you're not in dev mode. Do you really want to have Spotlight enabled?");
diff --git a/packages/replay-canvas/src/canvas.ts b/packages/replay-canvas/src/canvas.ts
index 04f91af7d578..5e3f5ab1b7bd 100644
--- a/packages/replay-canvas/src/canvas.ts
+++ b/packages/replay-canvas/src/canvas.ts
@@ -66,8 +66,6 @@ export const _replayCanvasIntegration = ((options: Partial<ReplayCanvasOptions>
 
   return {
     name: INTEGRATION_NAME,
-    // eslint-disable-next-line @typescript-eslint/no-empty-function
-    setupOnce() {},
     getOptions(): ReplayCanvasIntegrationOptions {
       const { quality, enableManualSnapshot } = _canvasOptions;
 
diff --git a/packages/types/src/integration.ts b/packages/types/src/integration.ts
index 3c3b44eb0ed8..543238ccc07b 100644
--- a/packages/types/src/integration.ts
+++ b/packages/types/src/integration.ts
@@ -24,10 +24,8 @@ export interface IntegrationFnResult {
   /**
    * This hook is only called once, even if multiple clients are created.
    * It does not receives any arguments, and should only use for e.g. global monkey patching and similar things.
-   *
-   * NOTE: In v8, this will become optional.
    */
-  setupOnce(): void;
+  setupOnce?(): void;
 
   /**
    * Set up an integration for the given client.
@@ -74,10 +72,8 @@ export interface Integration {
   /**
    * This hook is only called once, even if multiple clients are created.
    * It does not receives any arguments, and should only use for e.g. global monkey patching and similar things.
-   *
-   * NOTE: In v8, this will become optional, and not receive any arguments anymore.
    */
-  setupOnce(addGlobalEventProcessor: (callback: EventProcessor) => void, getCurrentHub: () => Hub): void;
+  setupOnce?(addGlobalEventProcessor: (callback: EventProcessor) => void, getCurrentHub: () => Hub): void;
 
   /**
    * Set up an integration for the given client.
diff --git a/packages/vercel-edge/src/integrations/wintercg-fetch.ts b/packages/vercel-edge/src/integrations/wintercg-fetch.ts
index 507a34aedab4..436e7f6f9b2d 100644
--- a/packages/vercel-edge/src/integrations/wintercg-fetch.ts
+++ b/packages/vercel-edge/src/integrations/wintercg-fetch.ts
@@ -87,8 +87,6 @@ const _winterCGFetch = ((options: Partial<Options> = {}) => {
 
   return {
     name: INTEGRATION_NAME,
-    // TODO v8: Remove this again
-    // eslint-disable-next-line @typescript-eslint/no-empty-function
     setupOnce() {
       addFetchInstrumentationHandler(handlerData => {
         const client = getClient();
diff --git a/packages/vercel-edge/test/wintercg-fetch.test.ts b/packages/vercel-edge/test/wintercg-fetch.test.ts
index 2121f037e479..f9e1c3ca8aed 100644
--- a/packages/vercel-edge/test/wintercg-fetch.test.ts
+++ b/packages/vercel-edge/test/wintercg-fetch.test.ts
@@ -43,7 +43,7 @@ describe('WinterCGFetch instrumentation', () => {
     addFetchInstrumentationHandlerSpy.mockImplementationOnce(() => undefined);
 
     const integration = winterCGFetchIntegration();
-    integration.setupOnce();
+    integration.setupOnce!();
     integration.setup!(client);
 
     const [fetchInstrumentationHandlerCallback] = addFetchInstrumentationHandlerSpy.mock.calls[0];
@@ -77,7 +77,7 @@ describe('WinterCGFetch instrumentation', () => {
     addFetchInstrumentationHandlerSpy.mockImplementationOnce(() => undefined);
 
     const integration = winterCGFetchIntegration();
-    integration.setupOnce();
+    integration.setupOnce!();
     // integration.setup!(client) is not called!
 
     const [fetchInstrumentationHandlerCallback] = addFetchInstrumentationHandlerSpy.mock.calls[0];
@@ -97,7 +97,7 @@ describe('WinterCGFetch instrumentation', () => {
     addFetchInstrumentationHandlerSpy.mockImplementationOnce(() => undefined);
 
     const integration = winterCGFetchIntegration();
-    integration.setupOnce();
+    integration.setupOnce!();
     integration.setup!(client);
 
     const [fetchInstrumentationHandlerCallback] = addFetchInstrumentationHandlerSpy.mock.calls[0];
@@ -121,7 +121,7 @@ describe('WinterCGFetch instrumentation', () => {
         return url === 'http://only-acceptable-url.com/';
       },
     });
-    integration.setupOnce();
+    integration.setupOnce!();
     integration.setup!(client);
 
     const [fetchInstrumentationHandlerCallback] = addFetchInstrumentationHandlerSpy.mock.calls[0];
@@ -145,7 +145,7 @@ describe('WinterCGFetch instrumentation', () => {
     addFetchInstrumentationHandlerSpy.mockImplementationOnce(() => undefined);
 
     const integration = winterCGFetchIntegration();
-    integration.setupOnce();
+    integration.setupOnce!();
     integration.setup!(client);
 
     const [fetchInstrumentationHandlerCallback] = addFetchInstrumentationHandlerSpy.mock.calls[0];
@@ -182,7 +182,7 @@ describe('WinterCGFetch instrumentation', () => {
     addFetchInstrumentationHandlerSpy.mockImplementationOnce(() => undefined);
 
     const integration = winterCGFetchIntegration({ breadcrumbs: false });
-    integration.setupOnce();
+    integration.setupOnce!();
     integration.setup!(client);
 
     const [fetchInstrumentationHandlerCallback] = addFetchInstrumentationHandlerSpy.mock.calls[0];
diff --git a/packages/vue/src/integration.ts b/packages/vue/src/integration.ts
index 4bd99e3d6c8c..bd528f276ab3 100644
--- a/packages/vue/src/integration.ts
+++ b/packages/vue/src/integration.ts
@@ -25,7 +25,6 @@ const _vueIntegration = ((integrationOptions: Partial<VueOptions> = {}) => {
   return {
     name: INTEGRATION_NAME,
     // TODO v8: Remove this
-    setupOnce() {}, // eslint-disable-line @typescript-eslint/no-empty-function
     setup(client) {
       _setupIntegration(client, integrationOptions);
     },