diff --git a/shell/common/shell.cc b/shell/common/shell.cc
index d6e94c6345362..136c09b9c39d0 100644
--- a/shell/common/shell.cc
+++ b/shell/common/shell.cc
@@ -419,6 +419,8 @@ Shell::Shell(DartVMRef vm,
       volatile_path_tracker_(std::move(volatile_path_tracker)),
       weak_factory_gpu_(nullptr),
       weak_factory_(this) {
+  FML_CHECK(!settings.enable_software_rendering || !settings.enable_impeller)
+      << "Software rendering is incompatible with Impeller.";
   FML_CHECK(vm_) << "Must have access to VM to create a shell.";
   FML_DCHECK(task_runners_.IsValid());
   FML_DCHECK(task_runners_.GetPlatformTaskRunner()->RunsTasksOnCurrentThread());
diff --git a/shell/common/shell_unittests.cc b/shell/common/shell_unittests.cc
index 4c4c85f8b768b..2c94ca7e7ad4b 100644
--- a/shell/common/shell_unittests.cc
+++ b/shell/common/shell_unittests.cc
@@ -4342,6 +4342,24 @@ TEST_F(ShellTest, PrintsErrorWhenPlatformMessageSentFromWrongThread) {
   ASSERT_FALSE(DartVMRef::IsInstanceRunning());
 }
 
+TEST_F(ShellTest, DiesIfSoftwareRenderingAndImpellerAreEnabledDeathTest) {
+#if defined(OS_FUCHSIA)
+  GTEST_SKIP() << "Fuchsia";
+#endif  // OS_FUCHSIA
+  ::testing::FLAGS_gtest_death_test_style = "threadsafe";
+  Settings settings = CreateSettingsForFixture();
+  settings.enable_impeller = true;
+  settings.enable_software_rendering = true;
+  ThreadHost thread_host("io.flutter.test." + GetCurrentTestName() + ".",
+                         ThreadHost::Type::Platform);
+  auto task_runner = thread_host.platform_thread->GetTaskRunner();
+  TaskRunners task_runners("test", task_runner, task_runner, task_runner,
+                           task_runner);
+  EXPECT_DEATH_IF_SUPPORTED(
+      CreateShell(settings, task_runners),
+      "Software rendering is incompatible with Impeller.");
+}
+
 }  // namespace testing
 }  // namespace flutter
 
diff --git a/testing/scenario_app/run_ios_tests.sh b/testing/scenario_app/run_ios_tests.sh
index 37ab3a76f11d0..f91a875feea22 100755
--- a/testing/scenario_app/run_ios_tests.sh
+++ b/testing/scenario_app/run_ios_tests.sh
@@ -78,13 +78,14 @@ echo "Running simulator tests with Impeller"
 echo ""
 
 # Skip testFontRenderingWhenSuppliedWithBogusFont: https://github.com/flutter/flutter/issues/113250
+# Skip golden tests that use software rendering: https://github.com/flutter/flutter/issues/131888
 if set -o pipefail && xcodebuild -sdk iphonesimulator \
   -scheme Scenarios \
   -resultBundlePath "$RESULT_BUNDLE_PATH/ios_scenario.xcresult" \
   -destination 'platform=iOS Simulator,OS=16.2,name=iPhone SE (3rd generation)' \
   clean test \
   FLUTTER_ENGINE="$FLUTTER_ENGINE" \
-  -skip-testing "ScenariosUITests/BogusFontTextTest/testFontRenderingWhenSuppliedWithBogusFont" \
+  -skip-testing "ScenariosUITests/BogusFontTextTest/testFontRenderingWhenSuppliedWithBogusFont,ScenarioUITests/PlatformViewMutationLargeClipRRectWithTransformTests/testPlatformView,ScenarioUITests/MultiplePlatformViewsTest/testPlatformView,ScenarioUITests/PlatformViewWithOtherBackdropFilterTests/testPlatformView,ScenarioUITests/TwoPlatformViewsWithOtherBackDropFilterTests/testPlatformView,ScenarioUITests/PlatformViewMutationClipPathTests/testPlatformView,ScenarioUITests/PlatformViewMutationClipRectWithTransformTests/testPlatformView,ScenarioUITests/PlatformViewGestureRecognizerTests/testRejectPolicyUtilTouchesEnded,ScenarioUITests/NonFullScreenFlutterViewPlatformViewUITests/testPlatformView,ScenarioUITests/PlatformViewUITests/testPlatformView,ScenarioUITests/PlatformViewMutationClipRectAfterMovedTests/testPlatformView,ScenarioUITests/PlatformViewMutationClipRectTests/testPlatformView,ScenarioUITests/TwoPlatformViewClipPathTests/testPlatformView,ScenarioUITests/MultiplePlatformViewsBackgroundForegroundTest/testPlatformView,ScenarioUITests/PlatformViewMutationOpacityTests/testPlatformView,ScenarioUITests/PlatformViewMutationClipRRectTests/testPlatformView,ScenarioUITests/PlatformViewMutationClipRRectWithTransformTests/testPlatformView,ScenarioUITests/PlatformViewMutationClipPathWithTransformTests/testPlatformView,ScenarioUITests/SpawnEngineTest/testSpawnEngineWorks,ScenarioUITests/PlatformViewRotation/testPlatformView,ScenarioUITests/TwoPlatformViewClipRRectTests/testPlatformView,ScenarioUITests/TwoPlatformViewClipRectTests/testPlatformView,ScenarioUITests/RenderingSelectionTest/testSoftwareRendering,ScenarioUITests/UnobstructedPlatformViewTests/testMultiplePlatformViewsWithOverlays,ScenarioUITests/UnobstructedPlatformViewTests/testNoOverlay,ScenarioUITests/PlatformViewMutationTransformTests/testPlatformView,ScenarioUITests/PlatformViewMutationLargeClipRRectTests/testPlatformView,ScenarioUITests/PlatformViewWithNegativeOtherBackDropFilterTests/testPlatformView" \
   INFOPLIST_FILE="Scenarios/Info_Impeller.plist"; then # Plist with FLTEnableImpeller=YES
   echo "test success."
 else