diff --git a/src/coreclr/jit/morph.cpp b/src/coreclr/jit/morph.cpp
index 0794b5ca8efa6d..b75173d3c19b59 100644
--- a/src/coreclr/jit/morph.cpp
+++ b/src/coreclr/jit/morph.cpp
@@ -14091,7 +14091,8 @@ GenTree* Compiler::fgMorphSmpOp(GenTree* tree, MorphAddrContext* mac)
             }
 
             // Fold "cmp & 1" to just "cmp"
-            if (tree->OperIs(GT_AND) && tree->TypeIs(TYP_INT) && op1->OperIsCompare() && op2->IsIntegralConst(1))
+            if (tree->OperIs(GT_AND) && tree->TypeIs(TYP_INT) && op1->OperIsCompare() && op2->IsIntegralConst(1) &&
+                !gtIsActiveCSE_Candidate(tree) && !gtIsActiveCSE_Candidate(op2))
             {
                 DEBUG_DESTROY_NODE(op2);
                 DEBUG_DESTROY_NODE(tree);