diff --git a/src/libraries/System.Runtime.Loader/tests/LoaderLinkTest.cs b/src/libraries/System.Runtime.Loader/tests/LoaderLinkTest.cs
index ff0f1b694c0bc6..069cc8c481a8c6 100644
--- a/src/libraries/System.Runtime.Loader/tests/LoaderLinkTest.cs
+++ b/src/libraries/System.Runtime.Loader/tests/LoaderLinkTest.cs
@@ -13,7 +13,7 @@ namespace LoaderLinkTest
 {
     public class LoaderLinkTest
     {
-        [Fact]
+        [ConditionalFact(typeof(PlatformDetection), nameof(PlatformDetection.HasAssemblyFiles))]
         public static void EnsureTypesLinked() // https://github.com/dotnet/runtime/issues/42207
         {
             string parentDir = Path.GetDirectoryName(Assembly.GetExecutingAssembly().Location);
diff --git a/src/libraries/System.Runtime.Loader/tests/SatelliteAssemblies.cs b/src/libraries/System.Runtime.Loader/tests/SatelliteAssemblies.cs
index 4f5e6265135795..e00166fa0be8de 100644
--- a/src/libraries/System.Runtime.Loader/tests/SatelliteAssemblies.cs
+++ b/src/libraries/System.Runtime.Loader/tests/SatelliteAssemblies.cs
@@ -74,7 +74,7 @@ public static IEnumerable<object[]> MainResources_TestData()
             }
         }
 
-        [Theory]
+        [ConditionalTheory(typeof(PlatformDetection), nameof(PlatformDetection.HasAssemblyFiles))]
         [MemberData(nameof(MainResources_TestData))]
         public static void mainResources(string lang, string expected)
         {
@@ -131,7 +131,7 @@ public static IEnumerable<object[]> DescribeLib_TestData()
             yield return new object[] { "ReferencedClassLibNeutralIsSatellite", "ReferencedClassLibNeutralIsSatellite.Program, ReferencedClassLibNeutralIsSatellite", "es",      "Neutral (es) language ReferencedClassLibNeutralIsSatellite description 1.0.0" };
         }
 
-        [ConditionalTheory(typeof(PlatformDetection), nameof(PlatformDetection.IsNotInvariantGlobalization))]
+        [ConditionalTheory(typeof(PlatformDetection), nameof(PlatformDetection.IsNotInvariantGlobalization), nameof(PlatformDetection.HasAssemblyFiles))]
         [MemberData(nameof(DescribeLib_TestData))]
         public void describeLib(string alc, string type, string culture, string expected)
         {
@@ -187,7 +187,7 @@ public static IEnumerable<object[]> SatelliteLoadsCorrectly_TestData()
             yield return new object[] { "ReferencedClassLibNeutralIsSatellite", "ReferencedClassLibNeutralIsSatellite", "es" };
         }
 
-        [ConditionalTheory(typeof(PlatformDetection), nameof(PlatformDetection.IsNotInvariantGlobalization))]
+        [ConditionalTheory(typeof(PlatformDetection), nameof(PlatformDetection.IsNotInvariantGlobalization), nameof(PlatformDetection.HasAssemblyFiles))]
         [MemberData(nameof(SatelliteLoadsCorrectly_TestData))]
         public void SatelliteLoadsCorrectly_FromName(string alc, string assemblyName, string culture)
         {
@@ -207,8 +207,8 @@ public void SatelliteLoadsCorrectly_FromName(string alc, string assemblyName, st
 
             Assert.Equal(culture, satelliteAssembly.GetName().CultureName);
         }
-        
-        [ConditionalTheory(typeof(PlatformDetection), nameof(PlatformDetection.IsNotInvariantGlobalization))]
+
+        [ConditionalTheory(typeof(PlatformDetection), nameof(PlatformDetection.IsNotInvariantGlobalization), nameof(PlatformDetection.HasAssemblyFiles))]
         [MemberData(nameof(SatelliteLoadsCorrectly_TestData))]
         public void SatelliteLoadsCorrectly_FromPath(string alc, string assemblyName, string culture)
         {
diff --git a/src/libraries/tests.proj b/src/libraries/tests.proj
index 70d328b46d033a..b88f2074cca52a 100644
--- a/src/libraries/tests.proj
+++ b/src/libraries/tests.proj
@@ -229,13 +229,13 @@
     <ProjectExclusions Include="$(MSBuildThisFileDirectory)System.Runtime\tests\System.Globalization.Tests\Invariant\Invariant.Tests.csproj" />
     <ProjectExclusions Include="$(MSBuildThisFileDirectory)System.Net.Http\tests\FunctionalTests\System.Net.Http.Functional.Tests.csproj" />
     <ProjectExclusions Include="$(MSBuildThisFileDirectory)System.Diagnostics.DiagnosticSource\tests\TestWithConfigSwitches\System.Diagnostics.DiagnosticSource.Switches.Tests.csproj" />
-    <ProjectExclusions Include="$(MSBuildThisFileDirectory)System.Reflection.MetadataLoadContext\tests\System.Reflection.MetadataLoadContext.Tests.csproj" />
     <ProjectExclusions Include="$(MSBuildThisFileDirectory)System.Runtime\tests\System.Resources.ResourceManager.Tests\System.Resources.ResourceManager.Tests.csproj" />
     <ProjectExclusions Include="$(MSBuildThisFileDirectory)System.Runtime\tests\System.Runtime.Tests\InvariantTimezone\System.Runtime.InvariantTimezone.Tests.csproj" />
-    <ProjectExclusions Include="$(MSBuildThisFileDirectory)System.Runtime.Loader\tests\System.Runtime.Loader.Tests.csproj" />
     <ProjectExclusions Include="$(MSBuildThisFileDirectory)System.Runtime\tests\System.Text.Encoding.Tests\System.Text.Encoding.Tests.csproj" />
     <!-- https://github.com/dotnet/runtime/issues/62547 -->
     <ProjectExclusions Include="$(MSBuildThisFileDirectory)System.Security.Cryptography\tests\System.Security.Cryptography.Tests.csproj" />
+    <!-- https://github.com/dotnet/runtime/issues/72908 -->
+    <ProjectExclusions Include="$(MSBuildThisFileDirectory)System.Reflection.MetadataLoadContext\tests\System.Reflection.MetadataLoadContext.Tests.csproj" />
   </ItemGroup>
 
   <ItemGroup Condition="'$(TargetOS)' == 'android' and '$(TargetArchitecture)' == 'x64' and '$(RuntimeFlavor)' == 'CoreCLR' and '$(RunDisablediOSTests)' != 'true'">