diff --git a/src/FSharp.Core/quotations.fs b/src/FSharp.Core/quotations.fs
index 0115811553a..338820c3f66 100644
--- a/src/FSharp.Core/quotations.fs
+++ b/src/FSharp.Core/quotations.fs
@@ -19,7 +19,6 @@ open Microsoft.FSharp.Text.StructuredPrintfImpl.Layout
 open Microsoft.FSharp.Text.StructuredPrintfImpl.TaggedText
 
 #nowarn "52" // The value has been copied to ensure the original is not mutated by this operation
-
 //--------------------------------------------------------------------------
 // RAW quotations - basic data types
 //--------------------------------------------------------------------------
@@ -1101,6 +1100,10 @@ module Patterns =
         let ty = FSharpType.MakeStructTupleType(asm, Array.map typeOf (Array.ofList args))
         mkFEN (NewTupleOp ty) args
 
+    let mkNewStructTupleNetStandard args =
+        let ty = FSharpType.MakeStructTupleType(Array.map typeOf (Array.ofList args))
+        mkFEN (NewTupleOp ty) args
+
     let mkTupleGet (ty, n, x) =
         checkTypesSR ty (typeOf x) "tupleGet" (SR.GetString(SR.QtmmExprNotMatchTuple))
         let mems = FSharpType.GetTupleElements ty
@@ -2586,6 +2589,9 @@ type Expr with
     static member NewStructTuple(asm: Assembly, elements) =
         mkNewStructTuple (asm, elements)
 
+    static member NewStructTuple elements =
+        mkNewStructTupleNetStandard elements
+
     static member NewRecord(recordType: Type, elements) =
         checkNonNull "recordType" recordType
         mkNewRecord (recordType, elements)
diff --git a/src/FSharp.Core/quotations.fsi b/src/FSharp.Core/quotations.fsi
index 5ec624e1438..7b689671c18 100644
--- a/src/FSharp.Core/quotations.fsi
+++ b/src/FSharp.Core/quotations.fsi
@@ -673,6 +673,22 @@ type Expr =
     /// </example>
     static member NewStructTuple: asm: Assembly * elements: Expr list -> Expr
 
+    /// <summary>Builds an expression that represents the creation of an F# tuple value</summary>
+    ///
+    /// <param name="elements">The list of elements of the tuple.</param>
+    ///
+    /// <returns>The resulting expression.</returns>
+    ///
+    /// <example id="newstructtuple-1">
+    /// <code lang="fsharp">
+    /// open FSharp.Quotations
+    ///
+    /// Expr.NewStructTuple( [ &lt;@ 1 @&gt;; &lt;@ "a" @&gt; ])
+    /// </code>
+    /// Evaluates to a quotation with the same structure as <c>&lt;@ struct (1, "a") @&gt;</c>.
+    /// </example>
+    static member NewStructTuple: elements: Expr list -> Expr
+
     /// <summary>Builds record-construction expressions </summary>
     ///
     /// <param name="recordType">The type of record.</param>
diff --git a/src/FSharp.Core/reflect.fs b/src/FSharp.Core/reflect.fs
index 6e0977e6edd..14726931473 100644
--- a/src/FSharp.Core/reflect.fs
+++ b/src/FSharp.Core/reflect.fs
@@ -628,27 +628,6 @@ module internal Impl =
 
     //-----------------------------------------------------------------
     // TUPLE DECOMPILATION
-    let tupleNames =
-        [|
-            "System.Tuple`1"
-            "System.Tuple`2"
-            "System.Tuple`3"
-            "System.Tuple`4"
-            "System.Tuple`5"
-            "System.Tuple`6"
-            "System.Tuple`7"
-            "System.Tuple`8"
-            "System.Tuple"
-            "System.ValueTuple`1"
-            "System.ValueTuple`2"
-            "System.ValueTuple`3"
-            "System.ValueTuple`4"
-            "System.ValueTuple`5"
-            "System.ValueTuple`6"
-            "System.ValueTuple`7"
-            "System.ValueTuple`8"
-            "System.ValueTuple"
-        |]
 
     let simpleTupleNames =
         [|
@@ -679,69 +658,137 @@ module internal Impl =
         // used in F# type providers.
         typ.IsGenericType
         && typ.Namespace = "System"
-        && simpleTupleNames |> Seq.exists typ.Name.StartsWith
+        && simpleTupleNames |> Array.exists typ.Name.StartsWith
 
     let maxTuple = 8
     // Which field holds the nested tuple?
     let tupleEncField = maxTuple - 1
 
-    let dictionaryLock = obj ()
-    let refTupleTypes = Dictionary<Assembly, Type[]>()
-    let valueTupleTypes = Dictionary<Assembly, Type[]>()
-
-    let rec mkTupleType isStruct (asm: Assembly) (tys: Type[]) =
-        let table =
-            let makeIt n =
-                let tupleFullName n =
-                    let structOffset = if isStruct then 9 else 0
-                    let index = n - 1 + structOffset
-                    tupleNames.[index]
-
-                match n with
-                | 1 -> asm.GetType(tupleFullName 1)
-                | 2 -> asm.GetType(tupleFullName 2)
-                | 3 -> asm.GetType(tupleFullName 3)
-                | 4 -> asm.GetType(tupleFullName 4)
-                | 5 -> asm.GetType(tupleFullName 5)
-                | 6 -> asm.GetType(tupleFullName 6)
-                | 7 -> asm.GetType(tupleFullName 7)
-                | 8 -> asm.GetType(tupleFullName 8)
-                | _ -> invalidArg "tys" (SR.GetString(SR.invalidTupleTypes))
-
-            let tables =
-                if isStruct then
-                    valueTupleTypes
-                else
-                    refTupleTypes
-
-            match lock dictionaryLock (fun () -> tables.TryGetValue asm) with
-            | false, _ ->
-                // the Dictionary<>s here could be ConcurrentDictionary<>'s, but then
-                // that would lock while initializing the Type array (maybe not an issue)
-                let mutable a = Array.init<Type> 8 (fun i -> makeIt (i + 1))
-
-                lock dictionaryLock (fun () ->
-                    match tables.TryGetValue asm with
-                    | true, t -> a <- t
-                    | false, _ -> tables.Add(asm, a))
-
-                a
-            | true, t -> t
-
-        match tys.Length with
-        | 1 -> table.[0].MakeGenericType tys
-        | 2 -> table.[1].MakeGenericType tys
-        | 3 -> table.[2].MakeGenericType tys
-        | 4 -> table.[3].MakeGenericType tys
-        | 5 -> table.[4].MakeGenericType tys
-        | 6 -> table.[5].MakeGenericType tys
-        | 7 -> table.[6].MakeGenericType tys
-        | n when n >= maxTuple ->
-            let tysA = tys.[0 .. tupleEncField - 1]
-            let tysB = tys.[maxTuple - 1 ..]
-            let tyB = mkTupleType isStruct asm tysB
-            table.[7].MakeGenericType(Array.append tysA [| tyB |])
-        | _ -> invalidArg "tys" (SR.GetString(SR.invalidTupleTypes))
+    module internal TupleFromSpecifiedAssembly =
+        let private tupleNames =
+            [|
+                "System.Tuple`1"
+                "System.Tuple`2"
+                "System.Tuple`3"
+                "System.Tuple`4"
+                "System.Tuple`5"
+                "System.Tuple`6"
+                "System.Tuple`7"
+                "System.Tuple`8"
+                "System.Tuple"
+                "System.ValueTuple`1"
+                "System.ValueTuple`2"
+                "System.ValueTuple`3"
+                "System.ValueTuple`4"
+                "System.ValueTuple`5"
+                "System.ValueTuple`6"
+                "System.ValueTuple`7"
+                "System.ValueTuple`8"
+                "System.ValueTuple"
+            |]
+
+        let private dictionaryLock = obj ()
+        let private refTupleTypes = Dictionary<Assembly, Type[]>()
+        let private valueTupleTypes = Dictionary<Assembly, Type[]>()
+
+        let rec mkTupleType isStruct (asm: Assembly) (tys: Type[]) =
+            let table =
+                let makeIt n =
+                    let tupleFullName n =
+                        let structOffset = if isStruct then 9 else 0
+                        let index = n - 1 + structOffset
+                        tupleNames.[index]
+
+                    match n with
+                    | 1 -> asm.GetType(tupleFullName 1)
+                    | 2 -> asm.GetType(tupleFullName 2)
+                    | 3 -> asm.GetType(tupleFullName 3)
+                    | 4 -> asm.GetType(tupleFullName 4)
+                    | 5 -> asm.GetType(tupleFullName 5)
+                    | 6 -> asm.GetType(tupleFullName 6)
+                    | 7 -> asm.GetType(tupleFullName 7)
+                    | 8 -> asm.GetType(tupleFullName 8)
+                    | _ -> invalidArg "tys" (SR.GetString(SR.invalidTupleTypes))
+
+                let tables =
+                    if isStruct then
+                        valueTupleTypes
+                    else
+                        refTupleTypes
+
+                match lock dictionaryLock (fun () -> tables.TryGetValue asm) with
+                | false, _ ->
+                    // the Dictionary<>s here could be ConcurrentDictionary<>'s, but then
+                    // that would lock while initializing the Type array (maybe not an issue)
+                    let mutable a = Array.init<Type> 8 (fun i -> makeIt (i + 1))
+
+                    lock dictionaryLock (fun () ->
+                        match tables.TryGetValue asm with
+                        | true, t -> a <- t
+                        | false, _ -> tables.Add(asm, a))
+
+                    a
+                | true, t -> t
+
+            match tys.Length with
+            | 1 -> table.[0].MakeGenericType tys
+            | 2 -> table.[1].MakeGenericType tys
+            | 3 -> table.[2].MakeGenericType tys
+            | 4 -> table.[3].MakeGenericType tys
+            | 5 -> table.[4].MakeGenericType tys
+            | 6 -> table.[5].MakeGenericType tys
+            | 7 -> table.[6].MakeGenericType tys
+            | n when n >= maxTuple ->
+                let tysA = tys.[0 .. tupleEncField - 1]
+                let tysB = tys.[maxTuple - 1 ..]
+                let tyB = mkTupleType isStruct asm tysB
+                table.[7].MakeGenericType(Array.append tysA [| tyB |])
+            | _ -> invalidArg "tys" (SR.GetString(SR.invalidTupleTypes))
+
+    let refTupleTypesNetStandard =
+        [|
+            typedefof<System.Tuple<_>>
+            typedefof<System.Tuple<_, _>>
+            typedefof<System.Tuple<_, _, _>>
+            typedefof<System.Tuple<_, _, _, _>>
+            typedefof<System.Tuple<_, _, _, _, _>>
+            typedefof<System.Tuple<_, _, _, _, _, _>>
+            typedefof<System.Tuple<_, _, _, _, _, _, _>>
+            typedefof<System.Tuple<_, _, _, _, _, _, _, _>>
+        |]
+
+    let structTupleTypesNetStandard =
+        [|
+            typedefof<System.ValueTuple<_>>
+            typedefof<System.ValueTuple<_, _>>
+            typedefof<System.ValueTuple<_, _, _>>
+            typedefof<System.ValueTuple<_, _, _, _>>
+            typedefof<System.ValueTuple<_, _, _, _, _>>
+            typedefof<System.ValueTuple<_, _, _, _, _, _>>
+            typedefof<System.ValueTuple<_, _, _, _, _, _, _>>
+            typedefof<System.ValueTuple<_, _, _, _, _, _, _, _>>
+        |]
+
+    /// Index of the recursively-nested Tuple type within the table of types
+    [<Literal>]
+    let nestedTupIndex = 7
+
+    /// Index of the last regular (non-nested) tuple type within the table of types
+    [<Literal>]
+    let lastRegularTupIndex = 6 //nestedTupIndex - 1 (wait for arithmetic in constants)
+
+    let rec mkTupleTypeNetStandard (tupTyTbl: Type[]) (tys: Type[]) =
+        let tblIdx = tys.Length - 1
+        assert (tblIdx >= 0)
+        assert (nestedTupIndex = tupTyTbl.Length - 1)
+
+        match tblIdx with
+        | idx when idx < nestedTupIndex -> tupTyTbl[ idx ].MakeGenericType tys
+        | _ ->
+            let tysA = tys.[0..lastRegularTupIndex]
+            let tysB = tys.[nestedTupIndex..]
+            let tyB = mkTupleTypeNetStandard tupTyTbl tysB
+            tupTyTbl.[nestedTupIndex].MakeGenericType([| yield! tysA; yield tyB |])
 
     let rec getTupleTypeInfo (typ: Type) =
         if not (isTupleType typ) then
@@ -1111,18 +1158,13 @@ type FSharpType =
     static member MakeTupleType(types: Type[]) =
         checkNonNull "types" types
 
-        // No assembly passed therefore just get framework local version of Tuple
-        let asm = typeof<System.Tuple>.Assembly
+        if types.Length = 0 then
+            invalidArg "types" (SR.GetString(SR.invalidTupleTypes))
 
-        if
-            types
-            |> Array.exists (function
-                | null -> true
-                | _ -> false)
-        then
+        if types |> Array.exists isNull then
             invalidArg "types" (SR.GetString(SR.nullsNotAllowedInArray))
 
-        mkTupleType false asm types
+        mkTupleTypeNetStandard refTupleTypesNetStandard types
 
     static member MakeTupleType(asm: Assembly, types: Type[]) =
         checkNonNull "types" types
@@ -1135,7 +1177,7 @@ type FSharpType =
         then
             invalidArg "types" (SR.GetString(SR.nullsNotAllowedInArray))
 
-        mkTupleType false asm types
+        TupleFromSpecifiedAssembly.mkTupleType false asm types
 
     static member MakeStructTupleType(asm: Assembly, types: Type[]) =
         checkNonNull "types" types
@@ -1148,7 +1190,18 @@ type FSharpType =
         then
             invalidArg "types" (SR.GetString(SR.nullsNotAllowedInArray))
 
-        mkTupleType true asm types
+        TupleFromSpecifiedAssembly.mkTupleType true asm types
+
+    static member MakeStructTupleType(types: Type[]) =
+        checkNonNull "types" types
+
+        if types.Length = 0 then
+            invalidArg "types" (SR.GetString(SR.invalidTupleTypes))
+
+        if types |> Array.exists isNull then
+            invalidArg "types" (SR.GetString(SR.nullsNotAllowedInArray))
+
+        mkTupleTypeNetStandard structTupleTypesNetStandard types
 
     static member GetTupleElements(tupleType: Type) =
         checkTupleType ("tupleType", tupleType)
diff --git a/src/FSharp.Core/reflect.fsi b/src/FSharp.Core/reflect.fsi
index 881c95331c9..6f528195ae5 100644
--- a/src/FSharp.Core/reflect.fsi
+++ b/src/FSharp.Core/reflect.fsi
@@ -619,6 +619,15 @@ type FSharpType =
     /// <example-tbd></example-tbd>
     static member MakeStructTupleType: asm: Assembly * types: Type[] -> Type
 
+    /// <summary>Returns a <see cref="T:System.Type"/> representing an F# struct tuple type with the given element types</summary>
+    ///
+    /// <param name="types">An array of types for the tuple elements.</param>
+    ///
+    /// <returns>The type representing the struct tuple containing the input elements.</returns>
+    ///
+    /// <example-tbd></example-tbd>
+    static member MakeStructTupleType: types: Type[] -> Type
+
     /// <summary>Return true if the <c>typ</c> is a representation of an F# tuple type </summary>
     ///
     /// <param name="typ">The type to check.</param>
diff --git a/tests/FSharp.Core.UnitTests/FSharp.Core.SurfaceArea.netstandard20.debug.bsl b/tests/FSharp.Core.UnitTests/FSharp.Core.SurfaceArea.netstandard20.debug.bsl
index b0ec5cbb925..7d0927147c0 100644
--- a/tests/FSharp.Core.UnitTests/FSharp.Core.SurfaceArea.netstandard20.debug.bsl
+++ b/tests/FSharp.Core.UnitTests/FSharp.Core.SurfaceArea.netstandard20.debug.bsl
@@ -2350,6 +2350,7 @@ Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr N
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewDelegate(System.Type, Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpVar], Microsoft.FSharp.Quotations.FSharpExpr)
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewObject(System.Reflection.ConstructorInfo, Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewRecord(System.Type, Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
+Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewStructTuple(Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewStructTuple(System.Reflection.Assembly, Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewTuple(Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewUnionCase(Microsoft.FSharp.Reflection.UnionCaseInfo, Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
@@ -2467,6 +2468,7 @@ Microsoft.FSharp.Reflection.FSharpType: System.Reflection.PropertyInfo[] GetReco
 Microsoft.FSharp.Reflection.FSharpType: System.Tuple`2[System.Type,System.Type] GetFunctionElements(System.Type)
 Microsoft.FSharp.Reflection.FSharpType: System.Type MakeFunctionType(System.Type, System.Type)
 Microsoft.FSharp.Reflection.FSharpType: System.Type MakeStructTupleType(System.Reflection.Assembly, System.Type[])
+Microsoft.FSharp.Reflection.FSharpType: System.Type MakeStructTupleType(System.Type[])
 Microsoft.FSharp.Reflection.FSharpType: System.Type MakeTupleType(System.Reflection.Assembly, System.Type[])
 Microsoft.FSharp.Reflection.FSharpType: System.Type MakeTupleType(System.Type[])
 Microsoft.FSharp.Reflection.FSharpType: System.Type[] GetTupleElements(System.Type)
diff --git a/tests/FSharp.Core.UnitTests/FSharp.Core.SurfaceArea.netstandard20.release.bsl b/tests/FSharp.Core.UnitTests/FSharp.Core.SurfaceArea.netstandard20.release.bsl
index bb1dd5db9d6..36b4f758dff 100644
--- a/tests/FSharp.Core.UnitTests/FSharp.Core.SurfaceArea.netstandard20.release.bsl
+++ b/tests/FSharp.Core.UnitTests/FSharp.Core.SurfaceArea.netstandard20.release.bsl
@@ -2349,6 +2349,7 @@ Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr N
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewDelegate(System.Type, Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpVar], Microsoft.FSharp.Quotations.FSharpExpr)
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewObject(System.Reflection.ConstructorInfo, Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewRecord(System.Type, Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
+Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewStructTuple(Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewStructTuple(System.Reflection.Assembly, Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewTuple(Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewUnionCase(Microsoft.FSharp.Reflection.UnionCaseInfo, Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
@@ -2466,6 +2467,7 @@ Microsoft.FSharp.Reflection.FSharpType: System.Reflection.PropertyInfo[] GetReco
 Microsoft.FSharp.Reflection.FSharpType: System.Tuple`2[System.Type,System.Type] GetFunctionElements(System.Type)
 Microsoft.FSharp.Reflection.FSharpType: System.Type MakeFunctionType(System.Type, System.Type)
 Microsoft.FSharp.Reflection.FSharpType: System.Type MakeStructTupleType(System.Reflection.Assembly, System.Type[])
+Microsoft.FSharp.Reflection.FSharpType: System.Type MakeStructTupleType(System.Type[])
 Microsoft.FSharp.Reflection.FSharpType: System.Type MakeTupleType(System.Reflection.Assembly, System.Type[])
 Microsoft.FSharp.Reflection.FSharpType: System.Type MakeTupleType(System.Type[])
 Microsoft.FSharp.Reflection.FSharpType: System.Type[] GetTupleElements(System.Type)
diff --git a/tests/FSharp.Core.UnitTests/FSharp.Core.SurfaceArea.netstandard21.debug.bsl b/tests/FSharp.Core.UnitTests/FSharp.Core.SurfaceArea.netstandard21.debug.bsl
index 028a4fee29b..fecb8627b97 100644
--- a/tests/FSharp.Core.UnitTests/FSharp.Core.SurfaceArea.netstandard21.debug.bsl
+++ b/tests/FSharp.Core.UnitTests/FSharp.Core.SurfaceArea.netstandard21.debug.bsl
@@ -2351,6 +2351,7 @@ Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr N
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewDelegate(System.Type, Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpVar], Microsoft.FSharp.Quotations.FSharpExpr)
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewObject(System.Reflection.ConstructorInfo, Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewRecord(System.Type, Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
+Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewStructTuple(Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewStructTuple(System.Reflection.Assembly, Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewTuple(Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewUnionCase(Microsoft.FSharp.Reflection.UnionCaseInfo, Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
@@ -2468,6 +2469,7 @@ Microsoft.FSharp.Reflection.FSharpType: System.Reflection.PropertyInfo[] GetReco
 Microsoft.FSharp.Reflection.FSharpType: System.Tuple`2[System.Type,System.Type] GetFunctionElements(System.Type)
 Microsoft.FSharp.Reflection.FSharpType: System.Type MakeFunctionType(System.Type, System.Type)
 Microsoft.FSharp.Reflection.FSharpType: System.Type MakeStructTupleType(System.Reflection.Assembly, System.Type[])
+Microsoft.FSharp.Reflection.FSharpType: System.Type MakeStructTupleType(System.Type[])
 Microsoft.FSharp.Reflection.FSharpType: System.Type MakeTupleType(System.Reflection.Assembly, System.Type[])
 Microsoft.FSharp.Reflection.FSharpType: System.Type MakeTupleType(System.Type[])
 Microsoft.FSharp.Reflection.FSharpType: System.Type[] GetTupleElements(System.Type)
diff --git a/tests/FSharp.Core.UnitTests/FSharp.Core.SurfaceArea.netstandard21.release.bsl b/tests/FSharp.Core.UnitTests/FSharp.Core.SurfaceArea.netstandard21.release.bsl
index 029951a590b..cd9e92fa8c6 100644
--- a/tests/FSharp.Core.UnitTests/FSharp.Core.SurfaceArea.netstandard21.release.bsl
+++ b/tests/FSharp.Core.UnitTests/FSharp.Core.SurfaceArea.netstandard21.release.bsl
@@ -2350,6 +2350,7 @@ Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr N
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewDelegate(System.Type, Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpVar], Microsoft.FSharp.Quotations.FSharpExpr)
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewObject(System.Reflection.ConstructorInfo, Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewRecord(System.Type, Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
+Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewStructTuple(Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewStructTuple(System.Reflection.Assembly, Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewTuple(Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
 Microsoft.FSharp.Quotations.FSharpExpr: Microsoft.FSharp.Quotations.FSharpExpr NewUnionCase(Microsoft.FSharp.Reflection.UnionCaseInfo, Microsoft.FSharp.Collections.FSharpList`1[Microsoft.FSharp.Quotations.FSharpExpr])
@@ -2467,6 +2468,7 @@ Microsoft.FSharp.Reflection.FSharpType: System.Reflection.PropertyInfo[] GetReco
 Microsoft.FSharp.Reflection.FSharpType: System.Tuple`2[System.Type,System.Type] GetFunctionElements(System.Type)
 Microsoft.FSharp.Reflection.FSharpType: System.Type MakeFunctionType(System.Type, System.Type)
 Microsoft.FSharp.Reflection.FSharpType: System.Type MakeStructTupleType(System.Reflection.Assembly, System.Type[])
+Microsoft.FSharp.Reflection.FSharpType: System.Type MakeStructTupleType(System.Type[])
 Microsoft.FSharp.Reflection.FSharpType: System.Type MakeTupleType(System.Reflection.Assembly, System.Type[])
 Microsoft.FSharp.Reflection.FSharpType: System.Type MakeTupleType(System.Type[])
 Microsoft.FSharp.Reflection.FSharpType: System.Type[] GetTupleElements(System.Type)
diff --git a/tests/FSharp.Core.UnitTests/FSharp.Core/Microsoft.FSharp.Quotations/FSharpQuotations.fs b/tests/FSharp.Core.UnitTests/FSharp.Core/Microsoft.FSharp.Quotations/FSharpQuotations.fs
index 02a3070d497..a8ea2816a73 100644
--- a/tests/FSharp.Core.UnitTests/FSharp.Core/Microsoft.FSharp.Quotations/FSharpQuotations.fs
+++ b/tests/FSharp.Core.UnitTests/FSharp.Core/Microsoft.FSharp.Quotations/FSharpQuotations.fs
@@ -120,6 +120,20 @@ type FSharpQuotationsTests() =
         | NewTuple [ Value(:? int as i, _) ; Value(:? string as s, _) ] when i = 1 && s = "" -> ()
         | _ -> Assert.Fail()
 
+    [<Fact>]
+    member x.``NewStructTuple without assembly should be recognized by NewStructTuple active pattern`` () =
+        let expr = Expr.NewStructTuple([ <@@ 1 @@>; <@@ "" @@> ])
+        match expr with
+        | NewStructTuple [ Value(:? int as i, _) ; Value(:? string as s, _) ] when i = 1 && s = "" -> ()
+        | _ -> Assert.Fail()
+
+    [<Fact>]
+    member x.``NewStructTuple without assembly should be recognized by NewTuple active pattern`` () =
+        let expr = Expr.NewStructTuple([ <@@ 1 @@>; <@@ "" @@> ])
+        match expr with
+        | NewTuple [ Value(:? int as i, _) ; Value(:? string as s, _) ] when i = 1 && s = "" -> ()
+        | _ -> Assert.Fail()
+
     [<Fact>]
     member x.``NewTuple should not be recognized by NewStructTuple active pattern`` () =
         let expr = Expr.NewTuple [ <@@ 1 @@>; <@@ "" @@> ]
diff --git a/tests/FSharp.Core.UnitTests/FSharp.Core/Microsoft.FSharp.Reflection/FSharpReflection.fs b/tests/FSharp.Core.UnitTests/FSharp.Core/Microsoft.FSharp.Reflection/FSharpReflection.fs
index ff1223b482a..987b779df17 100644
--- a/tests/FSharp.Core.UnitTests/FSharp.Core/Microsoft.FSharp.Reflection/FSharpReflection.fs
+++ b/tests/FSharp.Core.UnitTests/FSharp.Core/Microsoft.FSharp.Reflection/FSharpReflection.fs
@@ -1164,6 +1164,24 @@ type FSharpTypeTests() =
         // null
         CheckThrowsArgumentException(fun () ->FSharpType.MakeStructTupleType(asm, [|null;null|]) |> ignore )
 
+    [<Fact>]
+    member _.MakeStructTupleTypeNoAsm() =          
+        // positive
+        Assert.AreEqual(FSharpType.MakeStructTupleType( [|typeof<System.String>; typeof<System.Int32>|]), typeof<struct (string * int)>)
+        // positive for nested tuple
+        Assert.AreEqual(FSharpType.MakeStructTupleType( [|for i in 1..10 -> typeof<System.Int32>|]), typeof<struct(int * int * int * int * int * int * int * int * int * int )>)
+        // the representations above and below are equivalent, as tuple types are nested from 8th element on
+        Assert.AreEqual(FSharpType.MakeStructTupleType( [|for i in 1..10 -> typeof<System.Int32>|]), typeof<ValueTuple<int, int, int, int, int, int, int, ValueTuple<int, int, int>>>)
+
+        
+        // negative
+        Assert.AreNotEqual(FSharpType.MakeStructTupleType( [|typeof<System.String>; typeof<System.Int32>|]), typeof<struct (string * int * string)>)
+        
+        // invalid cases
+        CheckThrowsArgumentException(fun () ->FSharpType.MakeStructTupleType( [|null;null|]) |> ignore )
+        CheckThrowsArgumentException(fun () ->FSharpType.MakeStructTupleType( null) |> ignore )
+        CheckThrowsArgumentException(fun () ->FSharpType.MakeStructTupleType( [| |]) |> ignore )
+
 type UnionCaseInfoTests() =    
     
     let singlenullarycaseunion = SingleNullaryCaseDiscUnion.SingleNullaryCaseTag
diff --git a/tests/projects/SelfContained_Trimming_Test/check.ps1 b/tests/projects/SelfContained_Trimming_Test/check.ps1
index 388ed50ae7e..5269bd2b6f4 100644
--- a/tests/projects/SelfContained_Trimming_Test/check.ps1
+++ b/tests/projects/SelfContained_Trimming_Test/check.ps1
@@ -14,7 +14,7 @@ if (-not ($output -eq $expected))
 }
 
 # Checking that FSharp.Core binary is of expected size (needs adjustments if test is updated).
-$expected_len = 246272  # In bytes
+$expected_len = 248320 # In bytes
 $file = Get-Item .\bin\Release\net7.0\win-x64\publish\FSharp.Core.dll
 $file_len = $file.Length
 if (-not ($file_len -eq $expected_len))