diff --git a/sql/catalyst/src/main/scala/org/apache/spark/sql/catalyst/optimizer/PropagateEmptyRelation.scala b/sql/catalyst/src/main/scala/org/apache/spark/sql/catalyst/optimizer/PropagateEmptyRelation.scala
index 15d4561b47a23..05b61638cf72c 100644
--- a/sql/catalyst/src/main/scala/org/apache/spark/sql/catalyst/optimizer/PropagateEmptyRelation.scala
+++ b/sql/catalyst/src/main/scala/org/apache/spark/sql/catalyst/optimizer/PropagateEmptyRelation.scala
@@ -19,6 +19,7 @@ package org.apache.spark.sql.catalyst.optimizer
 
 import org.apache.spark.sql.catalyst.analysis.CastSupport
 import org.apache.spark.sql.catalyst.expressions._
+import org.apache.spark.sql.catalyst.expressions.Literal.FalseLiteral
 import org.apache.spark.sql.catalyst.plans._
 import org.apache.spark.sql.catalyst.plans.logical._
 import org.apache.spark.sql.catalyst.rules._
@@ -30,6 +31,7 @@ import org.apache.spark.sql.catalyst.rules._
  *    - Join with one or two empty children (including Intersect/Except).
  * 2. Unary-node Logical Plans
  *    - Project/Filter/Sample/Join/Limit/Repartition with all empty children.
+ *    - Join with false condition.
  *    - Aggregate with all empty children and at least one grouping expression.
  *    - Generate(Explode) with all empty children. Others like Hive UDTF may return results.
  */
@@ -71,24 +73,32 @@ object PropagateEmptyRelation extends Rule[LogicalPlan] with PredicateHelper wit
     // Joins on empty LocalRelations generated from streaming sources are not eliminated
     // as stateful streaming joins need to perform other state management operations other than
     // just processing the input data.
-    case p @ Join(_, _, joinType, _, _)
+    case p @ Join(_, _, joinType, conditionOpt, _)
         if !p.children.exists(_.isStreaming) =>
       val isLeftEmpty = isEmptyLocalRelation(p.left)
       val isRightEmpty = isEmptyLocalRelation(p.right)
-      if (isLeftEmpty || isRightEmpty) {
+      val isFalseCondition = conditionOpt match {
+        case Some(FalseLiteral) => true
+        case _ => false
+      }
+      if (isLeftEmpty || isRightEmpty || isFalseCondition) {
         joinType match {
           case _: InnerLike => empty(p)
           // Intersect is handled as LeftSemi by `ReplaceIntersectWithSemiJoin` rule.
           // Except is handled as LeftAnti by `ReplaceExceptWithAntiJoin` rule.
           case LeftOuter | LeftSemi | LeftAnti if isLeftEmpty => empty(p)
-          case LeftSemi if isRightEmpty => empty(p)
-          case LeftAnti if isRightEmpty => p.left
+          case LeftSemi if isRightEmpty | isFalseCondition => empty(p)
+          case LeftAnti if isRightEmpty | isFalseCondition => p.left
           case FullOuter if isLeftEmpty && isRightEmpty => empty(p)
           case LeftOuter | FullOuter if isRightEmpty =>
             Project(p.left.output ++ nullValueProjectList(p.right), p.left)
           case RightOuter if isRightEmpty => empty(p)
           case RightOuter | FullOuter if isLeftEmpty =>
             Project(nullValueProjectList(p.left) ++ p.right.output, p.right)
+          case LeftOuter if isFalseCondition =>
+            Project(p.left.output ++ nullValueProjectList(p.right), p.left)
+          case RightOuter if isFalseCondition =>
+            Project(nullValueProjectList(p.left) ++ p.right.output, p.right)
           case _ => p
         }
       } else {
diff --git a/sql/catalyst/src/test/scala/org/apache/spark/sql/catalyst/optimizer/PropagateEmptyRelationSuite.scala b/sql/catalyst/src/test/scala/org/apache/spark/sql/catalyst/optimizer/PropagateEmptyRelationSuite.scala
index 54c692c13b781..b5dcb8aa67646 100644
--- a/sql/catalyst/src/test/scala/org/apache/spark/sql/catalyst/optimizer/PropagateEmptyRelationSuite.scala
+++ b/sql/catalyst/src/test/scala/org/apache/spark/sql/catalyst/optimizer/PropagateEmptyRelationSuite.scala
@@ -22,6 +22,7 @@ import org.apache.spark.sql.catalyst.{CatalystTypeConverters, InternalRow}
 import org.apache.spark.sql.catalyst.dsl.expressions._
 import org.apache.spark.sql.catalyst.dsl.plans._
 import org.apache.spark.sql.catalyst.expressions.Literal
+import org.apache.spark.sql.catalyst.expressions.Literal.FalseLiteral
 import org.apache.spark.sql.catalyst.plans._
 import org.apache.spark.sql.catalyst.plans.logical.{LocalRelation, LogicalPlan, Project}
 import org.apache.spark.sql.catalyst.rules.RuleExecutor
@@ -155,6 +156,28 @@ class PropagateEmptyRelationSuite extends PlanTest {
     }
   }
 
+  test("SPARK-28220: Propagate empty relation through Join if condition is FalseLiteral") {
+    val testcases = Seq(
+      (Inner, Some(LocalRelation('a.int, 'b.int))),
+      (Cross, Some(LocalRelation('a.int, 'b.int))),
+      (LeftOuter,
+        Some(Project(Seq('a, Literal(null).cast(IntegerType).as('b)), testRelation1).analyze)),
+      (RightOuter,
+        Some(Project(Seq(Literal(null).cast(IntegerType).as('a), 'b), testRelation2).analyze)),
+      (FullOuter, None),
+      (LeftAnti, Some(testRelation1)),
+      (LeftSemi, Some(LocalRelation('a.int)))
+    )
+
+    testcases.foreach { case (jt, answer) =>
+      val query = testRelation1.join(testRelation2, joinType = jt, condition = Some(FalseLiteral))
+      val optimized = Optimize.execute(query.analyze)
+      val correctAnswer =
+        answer.getOrElse(OptimizeWithoutPropagateEmptyRelation.execute(query.analyze))
+      comparePlans(optimized, correctAnswer)
+    }
+  }
+
   test("propagate empty relation through UnaryNode") {
     val query = testRelation1
       .where(false)