diff --git a/src/aria/combobox/BUILD.bazel b/src/aria/combobox/BUILD.bazel
index be11bac48c0c..410b5174c435 100644
--- a/src/aria/combobox/BUILD.bazel
+++ b/src/aria/combobox/BUILD.bazel
@@ -12,6 +12,7 @@ ng_project(
         "//:node_modules/@angular/core",
         "//src/aria/deferred-content",
         "//src/aria/ui-patterns",
+        "//src/cdk/bidi",
     ],
 )
 
diff --git a/src/aria/combobox/combobox.ts b/src/aria/combobox/combobox.ts
index de5ed5d008d8..2c0af9581db7 100644
--- a/src/aria/combobox/combobox.ts
+++ b/src/aria/combobox/combobox.ts
@@ -24,6 +24,8 @@ import {
   ComboboxListboxControls,
   ComboboxTreeControls,
 } from '@angular/aria/ui-patterns';
+import {Directionality} from '@angular/cdk/bidi';
+import {toSignal} from '@angular/core/rxjs-interop';
 
 @Directive({
   selector: '[ngCombobox]',
@@ -44,6 +46,14 @@ import {
   },
 })
 export class Combobox<V> {
+  /** The directionality (LTR / RTL) context for the application (or a subtree of it). */
+  private readonly _directionality = inject(Directionality);
+
+  /** A signal wrapper for directionality. */
+  protected textDirection = toSignal(this._directionality.change, {
+    initialValue: this._directionality.value,
+  });
+
   /** The element that the combobox is attached to. */
   private readonly _elementRef = inject(ElementRef);
 
@@ -59,15 +69,24 @@ export class Combobox<V> {
   /** Whether the combobox is focused. */
   readonly isFocused = signal(false);
 
-  /** The value of the first matching item in the popup. */
-  firstMatch = input<V | undefined>(undefined);
-
   /** Whether the listbox has received focus yet. */
   private _hasBeenFocused = signal(false);
 
+  /** Whether the combobox is disabled. */
+  readonly disabled = input(false);
+
+  /** Whether the combobox is read-only. */
+  readonly readonly = input(false);
+
+  /** The value of the first matching item in the popup. */
+  readonly firstMatch = input<V | undefined>(undefined);
+
   /** The combobox ui pattern. */
   readonly pattern = new ComboboxPattern<any, V>({
     ...this,
+    textDirection: this.textDirection,
+    disabled: this.disabled,
+    readonly: this.readonly,
     inputValue: signal(''),
     inputEl: signal(undefined),
     containerEl: () => this._elementRef.nativeElement,
diff --git a/src/aria/ui-patterns/combobox/combobox.spec.ts b/src/aria/ui-patterns/combobox/combobox.spec.ts
index 8a67d3f0ce70..2a68aac363c1 100644
--- a/src/aria/ui-patterns/combobox/combobox.spec.ts
+++ b/src/aria/ui-patterns/combobox/combobox.spec.ts
@@ -97,6 +97,9 @@ function getComboboxPattern(
   const inputValue = signal('');
 
   const combobox = new ComboboxPattern<any, string>({
+    disabled: signal(inputs.disabled ?? false),
+    readonly: signal(inputs.readonly ?? false),
+    textDirection: signal(inputs.textDirection ?? 'ltr'),
     popupControls: signal(undefined), // will be set later
     inputEl,
     containerEl,
@@ -349,6 +352,13 @@ describe('Combobox with Listbox Pattern', () => {
 
       expect(combobox.expanded()).toBe(true);
     });
+
+    it('should not expand when disabled', () => {
+      const {combobox, inputEl} = getPatterns({disabled: true});
+      expect(combobox.expanded()).toBe(false);
+      combobox.onPointerup(clickInput(inputEl));
+      expect(combobox.expanded()).toBe(false);
+    });
   });
 
   describe('Selection', () => {
diff --git a/src/aria/ui-patterns/combobox/combobox.ts b/src/aria/ui-patterns/combobox/combobox.ts
index cb2c356822cc..9d8163d68db5 100644
--- a/src/aria/ui-patterns/combobox/combobox.ts
+++ b/src/aria/ui-patterns/combobox/combobox.ts
@@ -30,6 +30,15 @@ export interface ComboboxInputs<T extends ListItem<V>, V> {
 
   /** The value of the first matching item in the popup. */
   firstMatch: SignalLike<V | undefined>;
+
+  /** Whether the combobox is disabled. */
+  disabled: SignalLike<boolean>;
+
+  /** Whether the combobox is read-only. */
+  readonly: SignalLike<boolean>;
+
+  /** Whether the combobox is in a right-to-left context. */
+  textDirection: SignalLike<'rtl' | 'ltr'>;
 }
 
 /** An interface that allows combobox popups to expose the necessary controls for the combobox. */
@@ -119,10 +128,12 @@ export class ComboboxPattern<T extends ListItem<V>, V> {
   isFocused = signal(false);
 
   /** The key used to navigate to the previous item in the list. */
-  expandKey = computed(() => 'ArrowRight'); // TODO: RTL support.
+  expandKey = computed(() => (this.inputs.textDirection() === 'rtl' ? 'ArrowLeft' : 'ArrowRight'));
 
   /** The key used to navigate to the next item in the list. */
-  collapseKey = computed(() => 'ArrowLeft'); // TODO: RTL support.
+  collapseKey = computed(() =>
+    this.inputs.textDirection() === 'rtl' ? 'ArrowRight' : 'ArrowLeft',
+  );
 
   /** The ID of the popup associated with the combobox. */
   popupId = computed(() => this.inputs.popupControls()?.id() || null);
@@ -133,6 +144,9 @@ export class ComboboxPattern<T extends ListItem<V>, V> {
   /** The ARIA role of the popup associated with the combobox. */
   hasPopup = computed(() => this.inputs.popupControls()?.role() || null);
 
+  /** Whether the combobox is interactive. */
+  isInteractive = computed(() => !this.inputs.disabled() && !this.inputs.readonly());
+
   /** The keydown event manager for the combobox. */
   keydown = computed(() => {
     if (!this.expanded()) {
@@ -204,16 +218,24 @@ export class ComboboxPattern<T extends ListItem<V>, V> {
 
   /** Handles keydown events for the combobox. */
   onKeydown(event: KeyboardEvent) {
-    this.keydown().handle(event);
+    if (this.isInteractive()) {
+      this.keydown().handle(event);
+    }
   }
 
   /** Handles pointerup events for the combobox. */
   onPointerup(event: PointerEvent) {
-    this.pointerup().handle(event);
+    if (this.isInteractive()) {
+      this.pointerup().handle(event);
+    }
   }
 
   /** Handles input events for the combobox. */
   onInput(event: Event) {
+    if (!this.isInteractive()) {
+      return;
+    }
+
     const inputEl = this.inputs.inputEl();
 
     if (!inputEl) {
@@ -233,12 +255,17 @@ export class ComboboxPattern<T extends ListItem<V>, V> {
     }
   }
 
+  /** Handles focus in events for the combobox. */
   onFocusIn() {
     this.isFocused.set(true);
   }
 
   /** Handles focus out events for the combobox. */
   onFocusOut(event: FocusEvent) {
+    if (this.inputs.disabled() || this.inputs.readonly()) {
+      return;
+    }
+
     if (
       !(event.relatedTarget instanceof HTMLElement) ||
       !this.inputs.containerEl()?.contains(event.relatedTarget)
@@ -261,6 +288,7 @@ export class ComboboxPattern<T extends ListItem<V>, V> {
     }
   }
 
+  /** The first matching item in the combobox. */
   firstMatch = computed(() => {
     // TODO(wagnermaciel): Consider whether we should not provide this default behavior for the
     // listbox. Instead, we may want to allow users to have no match so that typing does not focus
@@ -275,6 +303,7 @@ export class ComboboxPattern<T extends ListItem<V>, V> {
       .find(i => i.value() === this.inputs.firstMatch());
   });
 
+  /** Handles filtering logic for the combobox. */
   onFilter() {
     // TODO(wagnermaciel)
     // When the user first interacts with the combobox, the popup will lazily render for the first
@@ -315,6 +344,7 @@ export class ComboboxPattern<T extends ListItem<V>, V> {
     }
   }
 
+  /** Highlights the currently selected item in the combobox. */
   highlight() {
     const inputEl = this.inputs.inputEl();
     const item = this.inputs.popupControls()?.getSelectedItem();
@@ -374,11 +404,13 @@ export class ComboboxPattern<T extends ListItem<V>, V> {
     this._navigate(() => this.inputs.popupControls()?.last());
   }
 
+  /** Collapses the currently focused item in the combobox. */
   collapseItem() {
     const controls = this.inputs.popupControls() as ComboboxTreeControls<T, V>;
     this._navigate(() => controls?.collapseItem());
   }
 
+  /** Expands the currently focused item in the combobox. */
   expandItem() {
     const controls = this.inputs.popupControls() as ComboboxTreeControls<T, V>;
     this._navigate(() => controls?.expandItem());