diff --git a/.github/workflows/Doxygen.yml b/.github/workflows/Doxygen.yml
index 6590403b26..ea1b1fc3e4 100644
--- a/.github/workflows/Doxygen.yml
+++ b/.github/workflows/Doxygen.yml
@@ -9,21 +9,24 @@ on:
 jobs:
   doxygen:
 
-    runs-on: ubuntu-latest
+    runs-on: ubuntu-24.04
 
     steps:
       - uses: actions/checkout@v4
         with:
           fetch-depth: 0
+
       - name: Build Docker Image for Doxygen
         run: |
           docker build -f Dockerfile -t itk-doxygen .
+
       - name: Docker Doxygen generation
         run: |
           docker run --name itk-dox itk-doxygen
           mkdir -p artifacts
           docker cp itk-dox:/ITKDoxygen.tar.gz artifacts/ITKDoxygen-${GITHUB_SHA}.tar.gz
           docker cp itk-dox:/ITKDoxygenXML.tar.gz artifacts/ITKDoxygenXML-${GITHUB_SHA}.tar.gz
+
       - name: Archive Doxygen Artifacts
         uses: actions/upload-artifact@v4
         with:
@@ -31,6 +34,31 @@ jobs:
           path: |
             artifacts/ITKDoxygenXML-*.tar.gz
             artifacts/ITKDoxygen-*.tar.gz
+
+      - name: Publish to latest GitHub Release
+        if: github.ref == 'refs/heads/main'
+        run: |
+          sudo apt install -y zstd
+
+          pushd artifacts
+
+          cp ITKDoxygen-*.tar.gz InsightDoxygenDocHtml-latest.tar.gz
+          gunzip InsightDoxygenDocHtml-latest.tar.gz
+          zstd -f -10 -T6 --long=31 InsightDoxygenDocHtml-latest.tar -o InsightDoxygenDocHtml-latest.tar.zst
+          gzip -9 InsightDoxygenDocHtml-latest.tar
+
+          cp ITKDoxygenXML-*.tar.gz InsightDoxygenDocXml-latest.tar.gz
+          gunzip InsightDoxygenDocXml-latest.tar.gz
+          zstd -f -10 -T6 --long=31 InsightDoxygenDocXml-latest.tar -o InsightDoxygenDocXml-latest.tar.zst
+          gzip -9 InsightDoxygenDocXml-latest.tar
+
+          popd
+
+          gh release delete -R InsightSoftwareConsortium/ITKDoxygen --cleanup-tag latest --yes
+          gh release create latest --notes="ITK Doxygen documentation built from the ITK master branch." --prerelease --title "ITKDoxygen Latest" -R InsightSoftwareConsortium/ITKDoxygen ./artifacts/InsightDoxygen*
+        env:
+          GH_TOKEN: ${{ secrets.github_token }}
+
       - name: Update gh-pages
         if: github.ref == 'refs/heads/main'
         run: |
diff --git a/.readthedocs.yaml b/.readthedocs.yaml
new file mode 100644
index 0000000000..3fbcb575dd
--- /dev/null
+++ b/.readthedocs.yaml
@@ -0,0 +1,22 @@
+# Read the Docs configuration file
+# See https://docs.readthedocs.io/en/stable/config-file/v2.html for details
+
+# Required
+version: 2
+
+# Set the OS, Python version, and other tools you might need
+build:
+  os: ubuntu-24.04
+  tools:
+    python: "mambaforge-23.11"
+
+  commands:
+    # Write down your commands here to:
+    #
+    #  - Install the dependencies of your project
+    #  - Build the documentation
+    #  - Save the generated files in $READTHEDOCS_OUTPUT/html
+    - mamba remove --force --name rtd --all
+    - mamba env create -f rtd-environment.yml
+    - mamba run -n rtd zstd --version
+    - ./rtd-download.sh
diff --git a/.rtd-publish-version b/.rtd-publish-version
new file mode 100644
index 0000000000..5845e34402
--- /dev/null
+++ b/.rtd-publish-version
@@ -0,0 +1 @@
+v5.2.0 2025-01-16-11-44-1737045882
diff --git a/README.md b/README.md
index 709eca36f1..a9d0dcd945 100644
--- a/README.md
+++ b/README.md
@@ -66,8 +66,8 @@ docker run \
 The following commands will copy the tarballs from the
 Docker container to your local working directory.
 ```shell
-docker cp itk-dox:/ITKDoxygen.tar.gz SimpleITKDoxygen${TAG:+-${TAG}}.tar.gz
-docker cp itk-dox:/ITKDoxygenXML.tar.gz SimpleITKDoxygenXML${TAG:+-${TAG}}.tar.gz
+docker cp itk-dox:/ITKDoxygen.tar.gz ITKDoxygen${TAG:+-${TAG}}.tar.gz
+docker cp itk-dox:/ITKDoxygenXML.tar.gz ITKDoxygenXML${TAG:+-${TAG}}.tar.gz
 
 # Remove the Docker container after copying the tarballs
 docker rm itk-dox
@@ -75,12 +75,12 @@ docker rm itk-dox
 
 ### 6. Extract the Doxygen Documentation
 Untar these tarballs to extract and verify the Doxygen documentation. 
-The `SimpleITKDoxygen` tarball contains the HTML documentation,
-while the `SimpleITKDoxygenXML` tarball contains the XML documentation.
+The `ITKDoxygen` tarball contains the HTML documentation,
+while the `ITKDoxygenXML` tarball contains the XML documentation.
 
 ```shell
-tar -xzf SimpleITKDoxygen${TAG:+-${TAG}}.tar.gz
-tar -xzf SimpleITKDoxygenXML${TAG:+-${TAG}}.tar.gz
+tar -xzf ITKDoxygen${TAG:+-${TAG}}.tar.gz
+tar -xzf ITKDoxygenXML${TAG:+-${TAG}}.tar.gz
 ```
 
-You may now view the Doxygen documentation by opening the `html/index.html` file.
\ No newline at end of file
+You may now view the Doxygen documentation by opening the `html/index.html` file.
diff --git a/rtd-download.sh b/rtd-download.sh
new file mode 100755
index 0000000000..684c32c5dc
--- /dev/null
+++ b/rtd-download.sh
@@ -0,0 +1,14 @@
+#!/usr/bin/env bash
+
+set -eox
+
+DOC_VERSION=$(if [[ "${READTHEDOCS_GIT_IDENTIFIER}" == *v* ]]; then echo "${READTHEDOCS_GIT_IDENTIFIER}"; else echo "latest"; fi)
+DOC_VERSION_NO_V=${DOC_VERSION//v/}
+curl -LO https://github.com/InsightSoftwareConsortium/ITKDoxygen/releases/download/${DOC_VERSION}/InsightDoxygenDocHtml-${DOC_VERSION_NO_V}.tar.zst
+
+mkdir -p $READTHEDOCS_OUTPUT
+unzstd --long=31 ./InsightDoxygenDocHtml-${DOC_VERSION_NO_V}.tar.zst
+tar xf \
+  ./InsightDoxygenDocHtml-${DOC_VERSION_NO_V}.tar \
+  -C $READTHEDOCS_OUTPUT
+
diff --git a/rtd-environment.yml b/rtd-environment.yml
new file mode 100644
index 0000000000..44136e8817
--- /dev/null
+++ b/rtd-environment.yml
@@ -0,0 +1,5 @@
+name: rtd
+channels:
+  - conda-forge
+dependencies:
+  - zstd